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The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria

Alterations in the polyamine and amino acid (tyrosine) moieties of philanthotoxin-343 (PhTX-343) were investigated for their effects on the antagonism of nicotinic acetylcholine receptors (nAChRs) isolated from the locust (Schistocerca gregaria) mushroom body. Through whole-cell patch-clamp recordin...

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Detalles Bibliográficos
Autores principales:	Luck, Victoria L., Richards, David P., Shaikh, Ashif Y., Franzyk, Henrik, Mellor, Ian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622278/ https://www.ncbi.nlm.nih.gov/pubmed/34834099 http://dx.doi.org/10.3390/molecules26227007

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