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Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review

Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been u...

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Autores principales: Khan, Muhammad Issa, Maqsood, Maria, Saeed, Raakia Anam, Alam, Amna, Sahar, Amna, Kieliszek, Marek, Miecznikowski, Antoni, Muzammil, Hafiz Shehzad, Aadil, Rana Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622323/
https://www.ncbi.nlm.nih.gov/pubmed/34833974
http://dx.doi.org/10.3390/molecules26226881
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author Khan, Muhammad Issa
Maqsood, Maria
Saeed, Raakia Anam
Alam, Amna
Sahar, Amna
Kieliszek, Marek
Miecznikowski, Antoni
Muzammil, Hafiz Shehzad
Aadil, Rana Muhammad
author_facet Khan, Muhammad Issa
Maqsood, Maria
Saeed, Raakia Anam
Alam, Amna
Sahar, Amna
Kieliszek, Marek
Miecznikowski, Antoni
Muzammil, Hafiz Shehzad
Aadil, Rana Muhammad
author_sort Khan, Muhammad Issa
collection PubMed
description Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of W. coagulans. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, W. coagulans also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of W. coagulans and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.
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spelling pubmed-86223232021-11-27 Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review Khan, Muhammad Issa Maqsood, Maria Saeed, Raakia Anam Alam, Amna Sahar, Amna Kieliszek, Marek Miecznikowski, Antoni Muzammil, Hafiz Shehzad Aadil, Rana Muhammad Molecules Article Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. Withania coagulans (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of W. coagulans. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, W. coagulans also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of W. coagulans and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases. MDPI 2021-11-15 /pmc/articles/PMC8622323/ /pubmed/34833974 http://dx.doi.org/10.3390/molecules26226881 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Khan, Muhammad Issa
Maqsood, Maria
Saeed, Raakia Anam
Alam, Amna
Sahar, Amna
Kieliszek, Marek
Miecznikowski, Antoni
Muzammil, Hafiz Shehzad
Aadil, Rana Muhammad
Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
title Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
title_full Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
title_fullStr Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
title_full_unstemmed Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
title_short Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
title_sort phytochemistry, food application, and therapeutic potential of the medicinal plant (withania coagulans): a review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622323/
https://www.ncbi.nlm.nih.gov/pubmed/34833974
http://dx.doi.org/10.3390/molecules26226881
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