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Reactivities of a Prostanoid EP2 Agonist, Omidenepag, Are Useful for Distinguishing between 3D Spheroids of Human Orbital Fibroblasts without or with Graves’ Orbitopathy

Background. To obtain new insights into the activation of the thyroid-stimulating hormone (TSH) and insulin-like growth factor 1 (IGF-1) receptors in human orbital fibroblasts (n-HOFs), the effects of the prostanoid EP2 agonist, omidenepag (OMD), and a rho-associated coiled-coil-containing protein k...

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Detalles Bibliográficos
Autores principales: Ida, Yosuke, Ichioka, Hanae, Furuhashi, Masato, Hikage, Fumihito, Watanabe, Megumi, Umetsu, Araya, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622545/
https://www.ncbi.nlm.nih.gov/pubmed/34831419
http://dx.doi.org/10.3390/cells10113196