Misfolded G Protein-Coupled Receptors and Endocrine Disease. Molecular Mechanisms and Therapeutic Prospects

Misfolding of G protein-coupled receptors (GPCRs) caused by mutations frequently leads to disease due to intracellular trapping of the conformationally abnormal receptor. Several endocrine diseases due to inactivating mutations in GPCRs have been described, including X-linked nephrogenic diabetes in...

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Detalles Bibliográficos
Autores principales: Ulloa-Aguirre, Alfredo, Zariñán, Teresa, Jardón-Valadez, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622668/
https://www.ncbi.nlm.nih.gov/pubmed/34830210
http://dx.doi.org/10.3390/ijms222212329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622668/
https://www.ncbi.nlm.nih.gov/pubmed/34830210
http://dx.doi.org/10.3390/ijms222212329

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