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To Discover the Efficient and Novel Drug Targets in Human Cancers Using CRISPR/Cas Screening and Databases

CRISPR/Cas has emerged as an excelle nt gene-editing technology and is used worldwide for research. The CRISPR library is an ideal tool for identifying essential genes and synthetic lethality targeted for cancer therapies in human cancers. Synthetic lethality is defined as multiple genetic abnormali...

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Detalles Bibliográficos
Autores principales: Onishi, Iichiroh, Yamamoto, Kouhei, Kinowaki, Yuko, Kitagawa, Masanobu, Kurata, Morito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622676/
https://www.ncbi.nlm.nih.gov/pubmed/34830205
http://dx.doi.org/10.3390/ijms222212322

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