Virtual Screening for Potential Phytobioactives as Therapeutic Leads to Inhibit NQO1 for Selective Anticancer Therapy

NAD(P)H:quinone acceptor oxidoreductase-1 (NQO1) is a ubiquitous flavin adenine dinucleotide-dependent flavoprotein that promotes obligatory two-electron reductions of quinones, quinonimines, nitroaromatics, and azo dyes. NQO1 is a multifunctional antioxidant enzyme whose expression and deletion are...

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Detalles Bibliográficos
Autores principales: Shreevatsa, Bhargav, Dharmashekara, Chandan, Swamy, Vikas Halasumane, Gowda, Meghana V., Achar, Raghu Ram, Kameshwar, Vivek Hamse, Thimmulappa, Rajesh Kumar, Syed, Asad, Elgorban, Abdallah M., Al-Rejaie, Salim S., Ortega-Castro, Joaquín, Frau, Juan, Flores-Holguín, Norma, Shivamallu, Chandan, Kollur, Shiva Prasad, Glossman-Mitnik, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622762/
https://www.ncbi.nlm.nih.gov/pubmed/34833955
http://dx.doi.org/10.3390/molecules26226863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622762/
https://www.ncbi.nlm.nih.gov/pubmed/34833955
http://dx.doi.org/10.3390/molecules26226863

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