Structural Effects of Disease-Related Mutations in Actin-Binding Period 3 of Tropomyosin

Tropomyosin (Tpm) is an actin-binding coiled-coil protein. In muscle, it regulates contractions in a troponin/Ca(2+)-dependent manner and controls the thin filament lengths at the pointed end. Due to its size and periodic structure, it is difficult to observe small local structural changes in the co...

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Detalles Bibliográficos
Autores principales: Kuruba, Balaganesh, Kaczmarek, Marta, Kęsik-Brodacka, Małgorzata, Fojutowska, Magdalena, Śliwinska, Małgorzata, Kostyukova, Alla S., Moraczewska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622905/
https://www.ncbi.nlm.nih.gov/pubmed/34834072
http://dx.doi.org/10.3390/molecules26226980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622905/
https://www.ncbi.nlm.nih.gov/pubmed/34834072
http://dx.doi.org/10.3390/molecules26226980

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