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Structural Effects of Disease-Related Mutations in Actin-Binding Period 3 of Tropomyosin
Tropomyosin (Tpm) is an actin-binding coiled-coil protein. In muscle, it regulates contractions in a troponin/Ca(2+)-dependent manner and controls the thin filament lengths at the pointed end. Due to its size and periodic structure, it is difficult to observe small local structural changes in the co...
Autores principales: | Kuruba, Balaganesh, Kaczmarek, Marta, Kęsik-Brodacka, Małgorzata, Fojutowska, Magdalena, Śliwinska, Małgorzata, Kostyukova, Alla S., Moraczewska, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622905/ https://www.ncbi.nlm.nih.gov/pubmed/34834072 http://dx.doi.org/10.3390/molecules26226980 |
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