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Improving the Efficacy of Antimicrobials against Biofilm-Embedded Bacteria Using Bovine Hyaluronidase Azoximer (Longidaza(®))

While in a biofilm, bacteria are extremely resistant to both antimicrobials and the immune system, leading to the development of chronic infection. Here, we show that bovine hyaluronidase fused with a copolymer of 1,4-ethylenepiperazine N-oxide and (N-carboxymethyl) -1,4-ethylenepiperazinium bromide...

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Detalles Bibliográficos
Autores principales:	Trizna, Elena, Baidamshina, Diana, Gorshkova, Anna, Drucker, Valentin, Bogachev, Mikhail, Tikhonov, Anton, Kayumov, Airat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622991/ https://www.ncbi.nlm.nih.gov/pubmed/34834156 http://dx.doi.org/10.3390/pharmaceutics13111740

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