A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry

Zika virus (ZIKV) is a re-emerging flavivirus that has caused large-scale epidemics. Infection during pregnancy can lead to neurologic developmental abnormalities in children. There is no approved vaccine or therapy for ZIKV. To uncover cellular pathways required for ZIKV that can be therapeutically...

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Detalles Bibliográficos
Autores principales: Luu, Anh Phuong, Yao, Zhenlan, Ramachandran, Sangeetha, Azzopardi, Stephanie A., Miles, Linde A., Schneider, William M., Hoffmann, H.-Heinrich, Bozzacco, Leonia, Garcia, Gustavo, Gong, Danyang, Damoiseaux, Robert, Tang, Hengli, Morizono, Kouki, Rudin, Charles M., Sun, Ren, Arumugaswami, Vaithilingaraja, Poirier, John T., MacDonald, Margaret R., Rice, Charles M., Li, Melody M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623001/
https://www.ncbi.nlm.nih.gov/pubmed/34834920
http://dx.doi.org/10.3390/v13112113

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