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The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients

The lung is a vital organ that houses the alveoli, which is where gas exchange takes place. The COVID-19 illness attacks lung cells directly, creating significant inflammation and resulting in their inability to function. To return to the nature of their job, it may be essential to rejuvenate the af...

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Autores principales: Abbas, Mohamed, Alqahtani, Mohammed S., Almohiy, Hussain M., Alqahtani, Fawaz F., Alhifzi, Roaa, Jambi, Layal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623030/
https://www.ncbi.nlm.nih.gov/pubmed/34833310
http://dx.doi.org/10.3390/polym13224011
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author Abbas, Mohamed
Alqahtani, Mohammed S.
Almohiy, Hussain M.
Alqahtani, Fawaz F.
Alhifzi, Roaa
Jambi, Layal K.
author_facet Abbas, Mohamed
Alqahtani, Mohammed S.
Almohiy, Hussain M.
Alqahtani, Fawaz F.
Alhifzi, Roaa
Jambi, Layal K.
author_sort Abbas, Mohamed
collection PubMed
description The lung is a vital organ that houses the alveoli, which is where gas exchange takes place. The COVID-19 illness attacks lung cells directly, creating significant inflammation and resulting in their inability to function. To return to the nature of their job, it may be essential to rejuvenate the afflicted lung cells. This is difficult because lung cells need a long time to rebuild and resume their function. Biopolymeric particles are the most effective means to transfer developing treatments to airway epithelial cells and then regenerate infected lung cells, which is one of the most significant symptoms connected with COVID-19. Delivering biocompatible and degradable natural biological materials, chemotherapeutic drugs, vaccines, proteins, antibodies, nucleic acids, and diagnostic agents are all examples of these molecules‘ usage. Furthermore, they are created by using several structural components, which allows them to effectively connect with these cells. We highlight their most recent uses in lung tissue regeneration in this review. These particles are classified into three groups: biopolymeric nanoparticles, biopolymeric stem cell materials, and biopolymeric scaffolds. The techniques and processes for regenerating lung tissue will be thoroughly explored.
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spelling pubmed-86230302021-11-27 The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients Abbas, Mohamed Alqahtani, Mohammed S. Almohiy, Hussain M. Alqahtani, Fawaz F. Alhifzi, Roaa Jambi, Layal K. Polymers (Basel) Review The lung is a vital organ that houses the alveoli, which is where gas exchange takes place. The COVID-19 illness attacks lung cells directly, creating significant inflammation and resulting in their inability to function. To return to the nature of their job, it may be essential to rejuvenate the afflicted lung cells. This is difficult because lung cells need a long time to rebuild and resume their function. Biopolymeric particles are the most effective means to transfer developing treatments to airway epithelial cells and then regenerate infected lung cells, which is one of the most significant symptoms connected with COVID-19. Delivering biocompatible and degradable natural biological materials, chemotherapeutic drugs, vaccines, proteins, antibodies, nucleic acids, and diagnostic agents are all examples of these molecules‘ usage. Furthermore, they are created by using several structural components, which allows them to effectively connect with these cells. We highlight their most recent uses in lung tissue regeneration in this review. These particles are classified into three groups: biopolymeric nanoparticles, biopolymeric stem cell materials, and biopolymeric scaffolds. The techniques and processes for regenerating lung tissue will be thoroughly explored. MDPI 2021-11-20 /pmc/articles/PMC8623030/ /pubmed/34833310 http://dx.doi.org/10.3390/polym13224011 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Abbas, Mohamed
Alqahtani, Mohammed S.
Almohiy, Hussain M.
Alqahtani, Fawaz F.
Alhifzi, Roaa
Jambi, Layal K.
The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients
title The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients
title_full The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients
title_fullStr The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients
title_full_unstemmed The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients
title_short The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 Patients
title_sort potential contribution of biopolymeric particles in lung tissue regeneration of covid-19 patients
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623030/
https://www.ncbi.nlm.nih.gov/pubmed/34833310
http://dx.doi.org/10.3390/polym13224011
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