Three-Component Synthesis of 2-Amino-3-cyano-4H-chromenes, In Silico Analysis of Their Pharmacological Profile, and In Vitro Anticancer and Antifungal Testing

Chromenes are compounds that may be useful for inhibiting topoisomerase and cytochrome, enzymes involved in the growth of cancer and fungal cells, respectively. The aim of this study was to synthesize a series of some novel 2-amino-3-cyano-4-aryl-6,7-methylendioxy-4H-chromenes 4a–o and 2-amino-3-cya...

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Detalles Bibliográficos
Autores principales: Feliciano, Alberto, Gómez-García, Omar, Escalante, Carlos H., Rodríguez-Hernández, Mario A., Vargas-Fuentes, Mariana, Andrade-Pavón, Dulce, Villa-Tanaca, Lourdes, Álvarez-Toledano, Cecilio, Ramírez-Apan, María Teresa, Vázquez, Miguel A., Tamariz, Joaquín, Delgado, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623194/
https://www.ncbi.nlm.nih.gov/pubmed/34832892
http://dx.doi.org/10.3390/ph14111110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623194/
https://www.ncbi.nlm.nih.gov/pubmed/34832892
http://dx.doi.org/10.3390/ph14111110

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