Cargando…
Three-Component Synthesis of 2-Amino-3-cyano-4H-chromenes, In Silico Analysis of Their Pharmacological Profile, and In Vitro Anticancer and Antifungal Testing
Chromenes are compounds that may be useful for inhibiting topoisomerase and cytochrome, enzymes involved in the growth of cancer and fungal cells, respectively. The aim of this study was to synthesize a series of some novel 2-amino-3-cyano-4-aryl-6,7-methylendioxy-4H-chromenes 4a–o and 2-amino-3-cya...
Autores principales: | Feliciano, Alberto, Gómez-García, Omar, Escalante, Carlos H., Rodríguez-Hernández, Mario A., Vargas-Fuentes, Mariana, Andrade-Pavón, Dulce, Villa-Tanaca, Lourdes, Álvarez-Toledano, Cecilio, Ramírez-Apan, María Teresa, Vázquez, Miguel A., Tamariz, Joaquín, Delgado, Francisco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623194/ https://www.ncbi.nlm.nih.gov/pubmed/34832892 http://dx.doi.org/10.3390/ph14111110 |
Ejemplares similares
-
Pyrrole-Based Enaminones as Building Blocks for the Synthesis of Indolizines and Pyrrolo[1,2-a]pyrazines Showing Potent Antifungal Activity
por: Miranda-Sánchez, Diter, et al.
Publicado: (2023) -
Synthesis, Molecular Docking, and Antimycotic Evaluation of Some 3-Acyl Imidazo[1,2-a]pyrimidines
por: Gómez-García, Omar, et al.
Publicado: (2018) -
Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of Candida glabrata (CgHMGR), Thus Decreasing Yeast Viability and Ergosterol Synthesis
por: Madrigal-Aguilar, Damián A., et al.
Publicado: (2022) -
4-Cyano-N-ethylspiro[chromene-2,4′-piperidine]-1′-carboxamide
por: Rajalakshmi, P., et al.
Publicado: (2012) -
Synthesis of New
Derivatives of Benzylidinemalononitrile
and Ethyl 2-Cyano-3-phenylacrylate: In Silico Anticancer Evaluation
por: Uddin, Kabir M., et al.
Publicado: (2023)