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Host Mesothelin Expression Increases Ovarian Cancer Metastasis in the Peritoneal Microenvironment

Mesothelin (MSLN), a glycoprotein normally expressed by mesothelial cells, is overexpressed in ovarian cancer (OvCa) suggesting a role in tumor progression, although the biological function is not fully understood. OvCa has a high mortality rate due to diagnosis at advanced stage disease with intrap...

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Detalles Bibliográficos
Autores principales: Hilliard, Tyvette S., Kowalski, Brooke, Iwamoto, Kyle, Agadi, Elizabeth A., Liu, Yueying, Yang, Jing, Asem, Marwa, Klymenko, Yuliya, Johnson, Jeff, Shi, Zonggao, Marfowaa, Gifty, Yemc, Madeleine G., Petrasko, Phillip, Stack, M. Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623331/
https://www.ncbi.nlm.nih.gov/pubmed/34830322
http://dx.doi.org/10.3390/ijms222212443