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Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey

During brain tumor resection surgery, it is essential to determine the tumor borders as the extent of resection is important for post-operative patient survival. The current process of removing a tissue sample for frozen section analysis has several shortcomings that might be overcome by confocal la...

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Autores principales: Fotteler, Marina L., Liesche-Starnecker, Friederike, Brielmaier, Maria C., Schobel, Johannes, Gempt, Jens, Schlegel, Jürgen, Swoboda, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623423/
https://www.ncbi.nlm.nih.gov/pubmed/34829475
http://dx.doi.org/10.3390/diagnostics11112128
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author Fotteler, Marina L.
Liesche-Starnecker, Friederike
Brielmaier, Maria C.
Schobel, Johannes
Gempt, Jens
Schlegel, Jürgen
Swoboda, Walter
author_facet Fotteler, Marina L.
Liesche-Starnecker, Friederike
Brielmaier, Maria C.
Schobel, Johannes
Gempt, Jens
Schlegel, Jürgen
Swoboda, Walter
author_sort Fotteler, Marina L.
collection PubMed
description During brain tumor resection surgery, it is essential to determine the tumor borders as the extent of resection is important for post-operative patient survival. The current process of removing a tissue sample for frozen section analysis has several shortcomings that might be overcome by confocal laser endomicroscopy (CLE). CLE is a promising new technology enabling the digital in vivo visualization of tissue structures in near real-time. Research on the socio-organizational impact of introducing this new methodology to routine care in neurosurgery and neuropathology is scarce. We analyzed a potential clinical workflow employing CLE by comparing it to the current process. Additionally, a small expert survey was conducted to collect data on the opinion of clinical staff working with CLE. While CLE can contribute to a workload reduction for neuropathologists and enable a shorter process and a more efficient use of resources, the effort for neurosurgeons and surgery assistants might increase. Experts agree that CLE offers huge potential for better diagnosis and therapy but also see challenges, especially due to the current state of experimental use, including a risk for misinterpretations and the need for special training. Future studies will show whether CLE can become part of routine care.
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spelling pubmed-86234232021-11-27 Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey Fotteler, Marina L. Liesche-Starnecker, Friederike Brielmaier, Maria C. Schobel, Johannes Gempt, Jens Schlegel, Jürgen Swoboda, Walter Diagnostics (Basel) Article During brain tumor resection surgery, it is essential to determine the tumor borders as the extent of resection is important for post-operative patient survival. The current process of removing a tissue sample for frozen section analysis has several shortcomings that might be overcome by confocal laser endomicroscopy (CLE). CLE is a promising new technology enabling the digital in vivo visualization of tissue structures in near real-time. Research on the socio-organizational impact of introducing this new methodology to routine care in neurosurgery and neuropathology is scarce. We analyzed a potential clinical workflow employing CLE by comparing it to the current process. Additionally, a small expert survey was conducted to collect data on the opinion of clinical staff working with CLE. While CLE can contribute to a workload reduction for neuropathologists and enable a shorter process and a more efficient use of resources, the effort for neurosurgeons and surgery assistants might increase. Experts agree that CLE offers huge potential for better diagnosis and therapy but also see challenges, especially due to the current state of experimental use, including a risk for misinterpretations and the need for special training. Future studies will show whether CLE can become part of routine care. MDPI 2021-11-16 /pmc/articles/PMC8623423/ /pubmed/34829475 http://dx.doi.org/10.3390/diagnostics11112128 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fotteler, Marina L.
Liesche-Starnecker, Friederike
Brielmaier, Maria C.
Schobel, Johannes
Gempt, Jens
Schlegel, Jürgen
Swoboda, Walter
Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey
title Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey
title_full Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey
title_fullStr Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey
title_full_unstemmed Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey
title_short Socio-Organizational Impact of Confocal Laser Endomicroscopy in Neurosurgery and Neuropathology: Results from a Process Analysis and Expert Survey
title_sort socio-organizational impact of confocal laser endomicroscopy in neurosurgery and neuropathology: results from a process analysis and expert survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623423/
https://www.ncbi.nlm.nih.gov/pubmed/34829475
http://dx.doi.org/10.3390/diagnostics11112128
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