Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020

The peste des petits ruminants virus (PPRV) mainly infects goats and sheep and causes a highly contagious disease, PPR. Recently, a PPRV strain named ChinaSX2020 was isolated and confirmed following an indirect immunofluorescence assay and PCR using PPRV-specific antibody and primers, respectively....

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Autores principales: Li, Lingxia, Wu, Jinyan, Cao, Xiaoan, He, Jijun, Liu, Xiangtao, Shang, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623451/
https://www.ncbi.nlm.nih.gov/pubmed/34822658
http://dx.doi.org/10.3390/vetsci8110285
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author Li, Lingxia
Wu, Jinyan
Cao, Xiaoan
He, Jijun
Liu, Xiangtao
Shang, Youjun
author_facet Li, Lingxia
Wu, Jinyan
Cao, Xiaoan
He, Jijun
Liu, Xiangtao
Shang, Youjun
author_sort Li, Lingxia
collection PubMed
description The peste des petits ruminants virus (PPRV) mainly infects goats and sheep and causes a highly contagious disease, PPR. Recently, a PPRV strain named ChinaSX2020 was isolated and confirmed following an indirect immunofluorescence assay and PCR using PPRV-specific antibody and primers, respectively. A sequencing of the ChinaSX2020 strain showed a genome length of 15,954 nucleotides. A phylogenetic tree analysis showed that the ChinaSX2020 genome was classified into lineage IV of the PRRV genotypes. The genome of the ChinaSX2020 strain was found to be closely related to PPRVs isolated in China between 2013 and 2014. These findings revealed that not a variety of PRRVs but similar PPRVs were continuously spreading and causing sporadic outbreaks in China.
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spelling pubmed-86234512021-11-27 Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020 Li, Lingxia Wu, Jinyan Cao, Xiaoan He, Jijun Liu, Xiangtao Shang, Youjun Vet Sci Brief Report The peste des petits ruminants virus (PPRV) mainly infects goats and sheep and causes a highly contagious disease, PPR. Recently, a PPRV strain named ChinaSX2020 was isolated and confirmed following an indirect immunofluorescence assay and PCR using PPRV-specific antibody and primers, respectively. A sequencing of the ChinaSX2020 strain showed a genome length of 15,954 nucleotides. A phylogenetic tree analysis showed that the ChinaSX2020 genome was classified into lineage IV of the PRRV genotypes. The genome of the ChinaSX2020 strain was found to be closely related to PPRVs isolated in China between 2013 and 2014. These findings revealed that not a variety of PRRVs but similar PPRVs were continuously spreading and causing sporadic outbreaks in China. MDPI 2021-11-22 /pmc/articles/PMC8623451/ /pubmed/34822658 http://dx.doi.org/10.3390/vetsci8110285 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Li, Lingxia
Wu, Jinyan
Cao, Xiaoan
He, Jijun
Liu, Xiangtao
Shang, Youjun
Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020
title Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020
title_full Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020
title_fullStr Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020
title_full_unstemmed Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020
title_short Analysis and Sequence Alignment of Peste des Petits Ruminants Virus ChinaSX2020
title_sort analysis and sequence alignment of peste des petits ruminants virus chinasx2020
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623451/
https://www.ncbi.nlm.nih.gov/pubmed/34822658
http://dx.doi.org/10.3390/vetsci8110285
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