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STAT6 Deficiency Attenuates Myeloid Fibroblast Activation and Macrophage Polarization in Experimental Folic Acid Nephropathy

Renal fibrosis is a pathologic feature of chronic kidney disease, which can lead to end-stage kidney disease. Myeloid fibroblasts play a central role in the pathogenesis of renal fibrosis. However, the molecular mechanisms pertaining to myeloid fibroblast activation remain to be elucidated. In the p...

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Detalles Bibliográficos
Autores principales: Jiao, Baihai, An, Changlong, Du, Hao, Tran, Melanie, Wang, Penghua, Zhou, Dong, Wang, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623460/
https://www.ncbi.nlm.nih.gov/pubmed/34831280
http://dx.doi.org/10.3390/cells10113057