Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature

There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as ‘poorly differentiated thyroid carcinoma’ (PDTC), or ‘insular carcinoma’, in view of the p...

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Autores principales: Bellini, Maria Irene, Biffoni, Marco, Patrone, Renato, Borcea, Maria Carola, Costanzo, Maria Ludovica, Garritano, Tiziana, Melcarne, Rossella, Menditto, Rosa, Metere, Alessio, Scorziello, Chiara, Summa, Marco, Ventrone, Luca, D’Andrea, Vito, Giacomelli, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623499/
https://www.ncbi.nlm.nih.gov/pubmed/34830540
http://dx.doi.org/10.3390/jcm10225258
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author Bellini, Maria Irene
Biffoni, Marco
Patrone, Renato
Borcea, Maria Carola
Costanzo, Maria Ludovica
Garritano, Tiziana
Melcarne, Rossella
Menditto, Rosa
Metere, Alessio
Scorziello, Chiara
Summa, Marco
Ventrone, Luca
D’Andrea, Vito
Giacomelli, Laura
author_facet Bellini, Maria Irene
Biffoni, Marco
Patrone, Renato
Borcea, Maria Carola
Costanzo, Maria Ludovica
Garritano, Tiziana
Melcarne, Rossella
Menditto, Rosa
Metere, Alessio
Scorziello, Chiara
Summa, Marco
Ventrone, Luca
D’Andrea, Vito
Giacomelli, Laura
author_sort Bellini, Maria Irene
collection PubMed
description There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as ‘poorly differentiated thyroid carcinoma’ (PDTC), or ‘insular carcinoma’, in view of the peculiar morphological characteristics of the cell groupings. The correct diagnosis and treatment of this entity have important prognostic and therapeutic significance. In this review, we describe the epidemiology, diagnosis, and management of PDTC and report our single centre experience to add to the limited evidence existing in the literature.
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spelling pubmed-86234992021-11-27 Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature Bellini, Maria Irene Biffoni, Marco Patrone, Renato Borcea, Maria Carola Costanzo, Maria Ludovica Garritano, Tiziana Melcarne, Rossella Menditto, Rosa Metere, Alessio Scorziello, Chiara Summa, Marco Ventrone, Luca D’Andrea, Vito Giacomelli, Laura J Clin Med Review There is controversy in the literature regarding a distinct subset of thyroid carcinoma whose histologically classification falls between well-differentiated and anaplastic carcinomas, previously identified as ‘poorly differentiated thyroid carcinoma’ (PDTC), or ‘insular carcinoma’, in view of the peculiar morphological characteristics of the cell groupings. The correct diagnosis and treatment of this entity have important prognostic and therapeutic significance. In this review, we describe the epidemiology, diagnosis, and management of PDTC and report our single centre experience to add to the limited evidence existing in the literature. MDPI 2021-11-12 /pmc/articles/PMC8623499/ /pubmed/34830540 http://dx.doi.org/10.3390/jcm10225258 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bellini, Maria Irene
Biffoni, Marco
Patrone, Renato
Borcea, Maria Carola
Costanzo, Maria Ludovica
Garritano, Tiziana
Melcarne, Rossella
Menditto, Rosa
Metere, Alessio
Scorziello, Chiara
Summa, Marco
Ventrone, Luca
D’Andrea, Vito
Giacomelli, Laura
Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
title Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
title_full Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
title_fullStr Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
title_full_unstemmed Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
title_short Poorly Differentiated Thyroid Carcinoma: Single Centre Experience and Review of the Literature
title_sort poorly differentiated thyroid carcinoma: single centre experience and review of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623499/
https://www.ncbi.nlm.nih.gov/pubmed/34830540
http://dx.doi.org/10.3390/jcm10225258
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