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Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI

Central fat accumulation is a significant determinant of cardio-metabolic health risk, known to differ between ethnically distinct human populations. Despite evidence for preferential central adiposity in Asian populations, the proportional distribution between the subcutaneous and visceral compartm...

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Autores principales: Kalimeri, Maria, Totman, John J., Baum, Thomas, Diefenbach, Maximilian N., Hauner, Hans, Makowski, Marcus R., Subburaj, Karupppasamy, Cameron-Smith, David, Henry, Christiani Jeyakumar, Karampinos, Dimitrios C., Junker, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623581/
https://www.ncbi.nlm.nih.gov/pubmed/34829474
http://dx.doi.org/10.3390/diagnostics11112127
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author Kalimeri, Maria
Totman, John J.
Baum, Thomas
Diefenbach, Maximilian N.
Hauner, Hans
Makowski, Marcus R.
Subburaj, Karupppasamy
Cameron-Smith, David
Henry, Christiani Jeyakumar
Karampinos, Dimitrios C.
Junker, Daniela
author_facet Kalimeri, Maria
Totman, John J.
Baum, Thomas
Diefenbach, Maximilian N.
Hauner, Hans
Makowski, Marcus R.
Subburaj, Karupppasamy
Cameron-Smith, David
Henry, Christiani Jeyakumar
Karampinos, Dimitrios C.
Junker, Daniela
author_sort Kalimeri, Maria
collection PubMed
description Central fat accumulation is a significant determinant of cardio-metabolic health risk, known to differ between ethnically distinct human populations. Despite evidence for preferential central adiposity in Asian populations, the proportional distribution between the subcutaneous and visceral compartments in Chinese postmenopausal women has not been thoroughly investigated. For this analysis, volumetrically quantified subcutaneous and visceral adipose tissue (SAT, VAT) in the pelvic and abdominal regions of postmenopausal Asian (Chinese-Singaporean) and Caucasian (German) women matched for age and Body Mass Index (BMI) was undertaken, to examine such differences between the two groups. Volumes were calculated from segmentations of magnetic resonance imaging datasets of the abdomen and pelvis. Despite SAT, VAT, and the corresponding total adipose tissue (TAT) being similar between the groups, VAT/SAT and VAT/TAT were higher in the Asian group (by 24.5% and 18.2%, respectively, each p = 0.02). Further, VAT/SAT and VAT/TAT were positively correlated with BMI in the Caucasian group only (p = 0.02 and p = 0.01, respectively). We concluded that VAT is proportionally higher in the non-obese Asian women, compared to the Caucasian women of matched age and BMI. This conclusion is in agreement with existing literature showing higher abdominal adiposity in Asian populations. Additionally, in the Asian group, BMI did not correlate with visceral adiposity on a significant level. Further analysis is required to examine the extent to which this increased VAT may impact cardio-metabolic health. There is, however, a need to emphasize healthy lifestyle behaviors in non-obese post-menopausal women of Chinese ancestry.
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spelling pubmed-86235812021-11-27 Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI Kalimeri, Maria Totman, John J. Baum, Thomas Diefenbach, Maximilian N. Hauner, Hans Makowski, Marcus R. Subburaj, Karupppasamy Cameron-Smith, David Henry, Christiani Jeyakumar Karampinos, Dimitrios C. Junker, Daniela Diagnostics (Basel) Article Central fat accumulation is a significant determinant of cardio-metabolic health risk, known to differ between ethnically distinct human populations. Despite evidence for preferential central adiposity in Asian populations, the proportional distribution between the subcutaneous and visceral compartments in Chinese postmenopausal women has not been thoroughly investigated. For this analysis, volumetrically quantified subcutaneous and visceral adipose tissue (SAT, VAT) in the pelvic and abdominal regions of postmenopausal Asian (Chinese-Singaporean) and Caucasian (German) women matched for age and Body Mass Index (BMI) was undertaken, to examine such differences between the two groups. Volumes were calculated from segmentations of magnetic resonance imaging datasets of the abdomen and pelvis. Despite SAT, VAT, and the corresponding total adipose tissue (TAT) being similar between the groups, VAT/SAT and VAT/TAT were higher in the Asian group (by 24.5% and 18.2%, respectively, each p = 0.02). Further, VAT/SAT and VAT/TAT were positively correlated with BMI in the Caucasian group only (p = 0.02 and p = 0.01, respectively). We concluded that VAT is proportionally higher in the non-obese Asian women, compared to the Caucasian women of matched age and BMI. This conclusion is in agreement with existing literature showing higher abdominal adiposity in Asian populations. Additionally, in the Asian group, BMI did not correlate with visceral adiposity on a significant level. Further analysis is required to examine the extent to which this increased VAT may impact cardio-metabolic health. There is, however, a need to emphasize healthy lifestyle behaviors in non-obese post-menopausal women of Chinese ancestry. MDPI 2021-11-16 /pmc/articles/PMC8623581/ /pubmed/34829474 http://dx.doi.org/10.3390/diagnostics11112127 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kalimeri, Maria
Totman, John J.
Baum, Thomas
Diefenbach, Maximilian N.
Hauner, Hans
Makowski, Marcus R.
Subburaj, Karupppasamy
Cameron-Smith, David
Henry, Christiani Jeyakumar
Karampinos, Dimitrios C.
Junker, Daniela
Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI
title Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI
title_full Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI
title_fullStr Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI
title_full_unstemmed Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI
title_short Postmenopausal Chinese-Singaporean Women Have a Higher Ratio of Visceral to Subcutaneous Adipose Tissue Volume than Caucasian Women of the Same Age and BMI
title_sort postmenopausal chinese-singaporean women have a higher ratio of visceral to subcutaneous adipose tissue volume than caucasian women of the same age and bmi
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623581/
https://www.ncbi.nlm.nih.gov/pubmed/34829474
http://dx.doi.org/10.3390/diagnostics11112127
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