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Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation

Infectious bronchitis virus (IBV) poses significant financial and biosecurity challenges to the commercial poultry farming industry. IBV is the causative agent of multi-systemic infection in the respiratory, reproductive and renal systems, which is similar to the symptoms of various viral and bacter...

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Autores principales: Bhuiyan, Md. Safiul Alam, Amin, Zarina, Rodrigues, Kenneth Francis, Saallah, Suryani, Shaarani, Sharifudin Md., Sarker, Subir, Siddiquee, Shafiquzzaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623603/
https://www.ncbi.nlm.nih.gov/pubmed/34822646
http://dx.doi.org/10.3390/vetsci8110273
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author Bhuiyan, Md. Safiul Alam
Amin, Zarina
Rodrigues, Kenneth Francis
Saallah, Suryani
Shaarani, Sharifudin Md.
Sarker, Subir
Siddiquee, Shafiquzzaman
author_facet Bhuiyan, Md. Safiul Alam
Amin, Zarina
Rodrigues, Kenneth Francis
Saallah, Suryani
Shaarani, Sharifudin Md.
Sarker, Subir
Siddiquee, Shafiquzzaman
author_sort Bhuiyan, Md. Safiul Alam
collection PubMed
description Infectious bronchitis virus (IBV) poses significant financial and biosecurity challenges to the commercial poultry farming industry. IBV is the causative agent of multi-systemic infection in the respiratory, reproductive and renal systems, which is similar to the symptoms of various viral and bacterial diseases reported in chickens. The avian immune system manifests the ability to respond to subsequent exposure with an antigen by stimulating mucosal, humoral and cell-mediated immunity. However, the immune response against IBV presents a dilemma due to the similarities between the different serotypes that infect poultry. Currently, the live attenuated and killed vaccines are applied for the control of IBV infection; however, the continual emergence of IB variants with rapidly evolving genetic variants increases the risk of outbreaks in intensive poultry farms. This review aims to focus on IBV challenge–infection, route and delivery of vaccines and vaccine-induced immune responses to IBV. Various commercial vaccines currently have been developed against IBV protection for accurate evaluation depending on the local situation. This review also highlights and updates the limitations in controlling IBV infection in poultry with issues pertaining to antiviral therapy and good biosecurity practices, which may aid in establishing good biorisk management protocols for its control and which will, in turn, result in a reduction in economic losses attributed to IBV infection.
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spelling pubmed-86236032021-11-27 Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation Bhuiyan, Md. Safiul Alam Amin, Zarina Rodrigues, Kenneth Francis Saallah, Suryani Shaarani, Sharifudin Md. Sarker, Subir Siddiquee, Shafiquzzaman Vet Sci Review Infectious bronchitis virus (IBV) poses significant financial and biosecurity challenges to the commercial poultry farming industry. IBV is the causative agent of multi-systemic infection in the respiratory, reproductive and renal systems, which is similar to the symptoms of various viral and bacterial diseases reported in chickens. The avian immune system manifests the ability to respond to subsequent exposure with an antigen by stimulating mucosal, humoral and cell-mediated immunity. However, the immune response against IBV presents a dilemma due to the similarities between the different serotypes that infect poultry. Currently, the live attenuated and killed vaccines are applied for the control of IBV infection; however, the continual emergence of IB variants with rapidly evolving genetic variants increases the risk of outbreaks in intensive poultry farms. This review aims to focus on IBV challenge–infection, route and delivery of vaccines and vaccine-induced immune responses to IBV. Various commercial vaccines currently have been developed against IBV protection for accurate evaluation depending on the local situation. This review also highlights and updates the limitations in controlling IBV infection in poultry with issues pertaining to antiviral therapy and good biosecurity practices, which may aid in establishing good biorisk management protocols for its control and which will, in turn, result in a reduction in economic losses attributed to IBV infection. MDPI 2021-11-12 /pmc/articles/PMC8623603/ /pubmed/34822646 http://dx.doi.org/10.3390/vetsci8110273 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bhuiyan, Md. Safiul Alam
Amin, Zarina
Rodrigues, Kenneth Francis
Saallah, Suryani
Shaarani, Sharifudin Md.
Sarker, Subir
Siddiquee, Shafiquzzaman
Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation
title Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation
title_full Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation
title_fullStr Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation
title_full_unstemmed Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation
title_short Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation
title_sort infectious bronchitis virus (gammacoronavirus) in poultry farming: vaccination, immune response and measures for mitigation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623603/
https://www.ncbi.nlm.nih.gov/pubmed/34822646
http://dx.doi.org/10.3390/vetsci8110273
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