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Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain

COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association betwee...

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Autores principales: Iguacel, Isabel, Maldonado, Aurelio Luna, Ruiz-Cabello, Aurelio Luna, Casaus, Marta, Moreno, Luis Alberto, Martínez-Jarreta, Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623604/
https://www.ncbi.nlm.nih.gov/pubmed/34835252
http://dx.doi.org/10.3390/vaccines9111321
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author Iguacel, Isabel
Maldonado, Aurelio Luna
Ruiz-Cabello, Aurelio Luna
Casaus, Marta
Moreno, Luis Alberto
Martínez-Jarreta, Begoña
author_facet Iguacel, Isabel
Maldonado, Aurelio Luna
Ruiz-Cabello, Aurelio Luna
Casaus, Marta
Moreno, Luis Alberto
Martínez-Jarreta, Begoña
author_sort Iguacel, Isabel
collection PubMed
description COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age.
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spelling pubmed-86236042021-11-27 Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain Iguacel, Isabel Maldonado, Aurelio Luna Ruiz-Cabello, Aurelio Luna Casaus, Marta Moreno, Luis Alberto Martínez-Jarreta, Begoña Vaccines (Basel) Article COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age. MDPI 2021-11-15 /pmc/articles/PMC8623604/ /pubmed/34835252 http://dx.doi.org/10.3390/vaccines9111321 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Iguacel, Isabel
Maldonado, Aurelio Luna
Ruiz-Cabello, Aurelio Luna
Casaus, Marta
Moreno, Luis Alberto
Martínez-Jarreta, Begoña
Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_full Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_fullStr Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_full_unstemmed Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_short Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain
title_sort association between covid-19 vaccine side effects and body mass index in spain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623604/
https://www.ncbi.nlm.nih.gov/pubmed/34835252
http://dx.doi.org/10.3390/vaccines9111321
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