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Icariin Protects H9c2 Rat Cardiomyoblasts from Doxorubicin-Induced Cardiotoxicity: Role of Caveolin-1 Upregulation and Enhanced Autophagic Response

Doxorubicin (Doxo) is a widely used antineoplastic drug which often induces cardiomyopathy, leading to congestive heart failure through the intramyocardial production of reactive oxygen species (ROS). Icariin (Ica) is a flavonoid isolated from Epimedii Herba (Berberidaceae). Some reports on the phar...

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Detalles Bibliográficos
Autores principales: Scicchitano, Miriam, Carresi, Cristina, Nucera, Saverio, Ruga, Stefano, Maiuolo, Jessica, Macrì, Roberta, Scarano, Federica, Bosco, Francesca, Mollace, Rocco, Cardamone, Antonio, Coppoletta, Anna Rita, Guarnieri, Lorenza, Zito, Maria Caterina, Bava, Irene, Cariati, Luca, Greco, Marta, Foti, Daniela Patrizia, Palma, Ernesto, Gliozzi, Micaela, Musolino, Vincenzo, Mollace, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623794/
https://www.ncbi.nlm.nih.gov/pubmed/34836326
http://dx.doi.org/10.3390/nu13114070