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Clinical Translation of Combined MAPK and Autophagy Inhibition in RAS Mutant Cancer
RAS (rat sarcoma virus) mutant cancers remain difficult to treat despite the advances in targeted therapy and immunotherapy. Targeted therapies against the components of mitogen-activated protein kinase (MAPK) pathways, including RAS, RAF, MEK, and ERK, have demonstrated activity in BRAF mutant and,...
Autores principales: | Lee, Jennifer J., Jain, Vaibhav, Amaravadi, Ravi K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623813/ https://www.ncbi.nlm.nih.gov/pubmed/34830283 http://dx.doi.org/10.3390/ijms222212402 |
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