Identification and Characterization of New Alu Element Insertion in the BRCA1 Exon 14 Associated with Hereditary Breast and Ovarian Cancer

Hereditary breast and ovarian cancer syndrome (HBOC) is an autosomal dominant cancer predisposition syndrome characterized by an increased risk of breast and ovarian cancers. Germline pathogenic variants in BRCA1 are found in about 7–10% of all familial breast cancers and 10% of ovarian cancers. Alu...

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Detalles Bibliográficos
Autores principales: Bouras, Ahmed, Leone, Melanie, Bonadona, Valerie, Lebrun, Marine, Calender, Alain, Boutry-Kryza, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623961/
https://www.ncbi.nlm.nih.gov/pubmed/34828342
http://dx.doi.org/10.3390/genes12111736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623961/
https://www.ncbi.nlm.nih.gov/pubmed/34828342
http://dx.doi.org/10.3390/genes12111736

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