Association of a Total Cholesterol Polygenic Score with Cholesterol Levels and Pathological Biomarkers across the Alzheimer’s Disease Spectrum

Midlife hypercholesterolemia is a well-known risk factor for sporadic Alzheimer’s disease (AD), and like AD, it is highly influenced by genetics with heritability estimates of 32–63%. We thus hypothesized that genetics underlying peripheral blood total cholesterol (TC) levels could influence the ris...

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Detalles Bibliográficos
Autores principales: Nilsson, Nathalie I. V., Picard, Cynthia, Labonté, Anne, Köbe, Theresa, Meyer, Pierre-François, Villeneuve, Sylvia, Auld, Daniel, Poirier, Judes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623969/
https://www.ncbi.nlm.nih.gov/pubmed/34828411
http://dx.doi.org/10.3390/genes12111805

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