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Association of a Total Cholesterol Polygenic Score with Cholesterol Levels and Pathological Biomarkers across the Alzheimer’s Disease Spectrum
Midlife hypercholesterolemia is a well-known risk factor for sporadic Alzheimer’s disease (AD), and like AD, it is highly influenced by genetics with heritability estimates of 32–63%. We thus hypothesized that genetics underlying peripheral blood total cholesterol (TC) levels could influence the ris...
Autores principales: | Nilsson, Nathalie I. V., Picard, Cynthia, Labonté, Anne, Köbe, Theresa, Meyer, Pierre-François, Villeneuve, Sylvia, Auld, Daniel, Poirier, Judes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623969/ https://www.ncbi.nlm.nih.gov/pubmed/34828411 http://dx.doi.org/10.3390/genes12111805 |
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