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Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells

Tumor cell crosstalk with platelets and, subsequently, their activation are key steps in hematogenous tumor metastasis. MACC1 is an oncogene involved in molecular pathogenesis of colorectal cancer (CRC) and other solid tumor entities, mediating motility and metastasis, making MACC1 an accepted progn...

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Detalles Bibliográficos
Autores principales: Haschemi, Reza, Kobelt, Dennis, Steinwarz, Elisabeth, Schlesinger, Martin, Stein, Ulrike, Bendas, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624049/
https://www.ncbi.nlm.nih.gov/pubmed/34830078
http://dx.doi.org/10.3390/ijms222212195