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Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature

With the rapid development of various coronavirus disease 2019 (COVID-19) vaccines in a bid to counter and contain the COVID-19 pandemic, unusual and uncommon side effects of COVID-19 vaccination have been increasingly reported in the literature. Ipsilateral lymphadenopathy is a fairly common side e...

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Autores principales: Tan, Hui Min, Hue, Susan Swee-Shan, Wee, Aileen, See, Kay Choong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624158/
https://www.ncbi.nlm.nih.gov/pubmed/34835182
http://dx.doi.org/10.3390/vaccines9111251
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author Tan, Hui Min
Hue, Susan Swee-Shan
Wee, Aileen
See, Kay Choong
author_facet Tan, Hui Min
Hue, Susan Swee-Shan
Wee, Aileen
See, Kay Choong
author_sort Tan, Hui Min
collection PubMed
description With the rapid development of various coronavirus disease 2019 (COVID-19) vaccines in a bid to counter and contain the COVID-19 pandemic, unusual and uncommon side effects of COVID-19 vaccination have been increasingly reported in the literature. Ipsilateral lymphadenopathy is a fairly common side effect of vaccination of any kind, with its etiology most commonly related to reactive lymphadenopathy. However, Kikuchi–Fujimoto Disease (KFD) or necrotizing histiocytic lymphadenitis is rarely observed post-vaccination, with only one other case of KFD post COVID-19 vaccination reported to date. We report two more cases of KFD post COVID-19 vaccination in the Asian population, highlighting the clinical course and salient clinical, radiological and histologic findings. In addition, we provide a literature review of the existing cases of lymphadenopathy post COVID-19 vaccination with cytologic and/or histologic correlation.
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spelling pubmed-86241582021-11-27 Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature Tan, Hui Min Hue, Susan Swee-Shan Wee, Aileen See, Kay Choong Vaccines (Basel) Case Report With the rapid development of various coronavirus disease 2019 (COVID-19) vaccines in a bid to counter and contain the COVID-19 pandemic, unusual and uncommon side effects of COVID-19 vaccination have been increasingly reported in the literature. Ipsilateral lymphadenopathy is a fairly common side effect of vaccination of any kind, with its etiology most commonly related to reactive lymphadenopathy. However, Kikuchi–Fujimoto Disease (KFD) or necrotizing histiocytic lymphadenitis is rarely observed post-vaccination, with only one other case of KFD post COVID-19 vaccination reported to date. We report two more cases of KFD post COVID-19 vaccination in the Asian population, highlighting the clinical course and salient clinical, radiological and histologic findings. In addition, we provide a literature review of the existing cases of lymphadenopathy post COVID-19 vaccination with cytologic and/or histologic correlation. MDPI 2021-10-29 /pmc/articles/PMC8624158/ /pubmed/34835182 http://dx.doi.org/10.3390/vaccines9111251 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Tan, Hui Min
Hue, Susan Swee-Shan
Wee, Aileen
See, Kay Choong
Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature
title Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature
title_full Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature
title_fullStr Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature
title_full_unstemmed Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature
title_short Kikuchi–Fujimoto Disease Post COVID-19 Vaccination: Case Report and Review of Literature
title_sort kikuchi–fujimoto disease post covid-19 vaccination: case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624158/
https://www.ncbi.nlm.nih.gov/pubmed/34835182
http://dx.doi.org/10.3390/vaccines9111251
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