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Conditional Invertible Neural Networks for Medical Imaging

Over recent years, deep learning methods have become an increasingly popular choice for solving tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point estimates for the reconstruction. However, especially in the...

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Autores principales: Denker, Alexander, Schmidt, Maximilian, Leuschner, Johannes, Maass, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624162/
https://www.ncbi.nlm.nih.gov/pubmed/34821874
http://dx.doi.org/10.3390/jimaging7110243
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author Denker, Alexander
Schmidt, Maximilian
Leuschner, Johannes
Maass, Peter
author_facet Denker, Alexander
Schmidt, Maximilian
Leuschner, Johannes
Maass, Peter
author_sort Denker, Alexander
collection PubMed
description Over recent years, deep learning methods have become an increasingly popular choice for solving tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point estimates for the reconstruction. However, especially in the analysis of ill-posed inverse problems, the study of uncertainties is essential. In our work, we apply generative flow-based models based on invertible neural networks to two challenging medical imaging tasks, i.e., low-dose computed tomography and accelerated medical resonance imaging. We test different architectures of invertible neural networks and provide extensive ablation studies. In most applications, a standard Gaussian is used as the base distribution for a flow-based model. Our results show that the choice of a radial distribution can improve the quality of reconstructions.
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spelling pubmed-86241622021-11-27 Conditional Invertible Neural Networks for Medical Imaging Denker, Alexander Schmidt, Maximilian Leuschner, Johannes Maass, Peter J Imaging Article Over recent years, deep learning methods have become an increasingly popular choice for solving tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point estimates for the reconstruction. However, especially in the analysis of ill-posed inverse problems, the study of uncertainties is essential. In our work, we apply generative flow-based models based on invertible neural networks to two challenging medical imaging tasks, i.e., low-dose computed tomography and accelerated medical resonance imaging. We test different architectures of invertible neural networks and provide extensive ablation studies. In most applications, a standard Gaussian is used as the base distribution for a flow-based model. Our results show that the choice of a radial distribution can improve the quality of reconstructions. MDPI 2021-11-17 /pmc/articles/PMC8624162/ /pubmed/34821874 http://dx.doi.org/10.3390/jimaging7110243 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Denker, Alexander
Schmidt, Maximilian
Leuschner, Johannes
Maass, Peter
Conditional Invertible Neural Networks for Medical Imaging
title Conditional Invertible Neural Networks for Medical Imaging
title_full Conditional Invertible Neural Networks for Medical Imaging
title_fullStr Conditional Invertible Neural Networks for Medical Imaging
title_full_unstemmed Conditional Invertible Neural Networks for Medical Imaging
title_short Conditional Invertible Neural Networks for Medical Imaging
title_sort conditional invertible neural networks for medical imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624162/
https://www.ncbi.nlm.nih.gov/pubmed/34821874
http://dx.doi.org/10.3390/jimaging7110243
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