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Conditional Invertible Neural Networks for Medical Imaging
Over recent years, deep learning methods have become an increasingly popular choice for solving tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point estimates for the reconstruction. However, especially in the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624162/ https://www.ncbi.nlm.nih.gov/pubmed/34821874 http://dx.doi.org/10.3390/jimaging7110243 |
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author | Denker, Alexander Schmidt, Maximilian Leuschner, Johannes Maass, Peter |
author_facet | Denker, Alexander Schmidt, Maximilian Leuschner, Johannes Maass, Peter |
author_sort | Denker, Alexander |
collection | PubMed |
description | Over recent years, deep learning methods have become an increasingly popular choice for solving tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point estimates for the reconstruction. However, especially in the analysis of ill-posed inverse problems, the study of uncertainties is essential. In our work, we apply generative flow-based models based on invertible neural networks to two challenging medical imaging tasks, i.e., low-dose computed tomography and accelerated medical resonance imaging. We test different architectures of invertible neural networks and provide extensive ablation studies. In most applications, a standard Gaussian is used as the base distribution for a flow-based model. Our results show that the choice of a radial distribution can improve the quality of reconstructions. |
format | Online Article Text |
id | pubmed-8624162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86241622021-11-27 Conditional Invertible Neural Networks for Medical Imaging Denker, Alexander Schmidt, Maximilian Leuschner, Johannes Maass, Peter J Imaging Article Over recent years, deep learning methods have become an increasingly popular choice for solving tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point estimates for the reconstruction. However, especially in the analysis of ill-posed inverse problems, the study of uncertainties is essential. In our work, we apply generative flow-based models based on invertible neural networks to two challenging medical imaging tasks, i.e., low-dose computed tomography and accelerated medical resonance imaging. We test different architectures of invertible neural networks and provide extensive ablation studies. In most applications, a standard Gaussian is used as the base distribution for a flow-based model. Our results show that the choice of a radial distribution can improve the quality of reconstructions. MDPI 2021-11-17 /pmc/articles/PMC8624162/ /pubmed/34821874 http://dx.doi.org/10.3390/jimaging7110243 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Denker, Alexander Schmidt, Maximilian Leuschner, Johannes Maass, Peter Conditional Invertible Neural Networks for Medical Imaging |
title | Conditional Invertible Neural Networks for Medical Imaging |
title_full | Conditional Invertible Neural Networks for Medical Imaging |
title_fullStr | Conditional Invertible Neural Networks for Medical Imaging |
title_full_unstemmed | Conditional Invertible Neural Networks for Medical Imaging |
title_short | Conditional Invertible Neural Networks for Medical Imaging |
title_sort | conditional invertible neural networks for medical imaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624162/ https://www.ncbi.nlm.nih.gov/pubmed/34821874 http://dx.doi.org/10.3390/jimaging7110243 |
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