Construction of a Nano-Controlled Release Methotrexate Delivery System for the Treatment of Rheumatoid Arthritis by Local Percutaneous Administration

A drug delivery system was specifically designed for the treatment of rheumatoid arthritis (RA) by local percutaneous administration and the nano-controlled release of methotrexate (MTX). The release behavior of MTX from the synthesized MTX-mSiO(2)@PDA system was investigated in vitro and in vivo. T...

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Detalles Bibliográficos
Autores principales: Guo, Tingting, Kang, Xu, Ren, Sifan, Ouyang, Xianjin, Chang, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624172/
https://www.ncbi.nlm.nih.gov/pubmed/34835577
http://dx.doi.org/10.3390/nano11112812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624172/
https://www.ncbi.nlm.nih.gov/pubmed/34835577
http://dx.doi.org/10.3390/nano11112812

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