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Construction of a Nano-Controlled Release Methotrexate Delivery System for the Treatment of Rheumatoid Arthritis by Local Percutaneous Administration

A drug delivery system was specifically designed for the treatment of rheumatoid arthritis (RA) by local percutaneous administration and the nano-controlled release of methotrexate (MTX). The release behavior of MTX from the synthesized MTX-mSiO(2)@PDA system was investigated in vitro and in vivo. T...

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Detalles Bibliográficos
Autores principales:	Guo, Tingting, Kang, Xu, Ren, Sifan, Ouyang, Xianjin, Chang, Mingming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624172/ https://www.ncbi.nlm.nih.gov/pubmed/34835577 http://dx.doi.org/10.3390/nano11112812

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