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Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology

Tissue pathogens are commonly encountered in histopathology and cytology practice, where they can present as either benign mimickers of malignancy or true malignancies. The aim of this review is to provide a timely synthesis of our understanding of these tissue pathogens, with an emphasis on pertine...

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Detalles Bibliográficos
Autores principales: Chua, Tzy Harn, Punjabi, Lavisha S, Khor, Li Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624235/
https://www.ncbi.nlm.nih.gov/pubmed/34832566
http://dx.doi.org/10.3390/pathogens10111410
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author Chua, Tzy Harn
Punjabi, Lavisha S
Khor, Li Yan
author_facet Chua, Tzy Harn
Punjabi, Lavisha S
Khor, Li Yan
author_sort Chua, Tzy Harn
collection PubMed
description Tissue pathogens are commonly encountered in histopathology and cytology practice, where they can present as either benign mimickers of malignancy or true malignancies. The aim of this review is to provide a timely synthesis of our understanding of these tissue pathogens, with an emphasis on pertinent diagnostic conundrums associated with the benign mimickers of malignancy that can be seen with viral infections and those which manifest as granulomas. The oncogenic pathogens, including viruses, bacteria, and parasites, are then discussed with relationship to their associated malignancies. Although not exhaustive, the epidemiology, clinical manifestations, pathogenesis, and histological findings are included, along with a short review of emerging therapies.
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spelling pubmed-86242352021-11-27 Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology Chua, Tzy Harn Punjabi, Lavisha S Khor, Li Yan Pathogens Review Tissue pathogens are commonly encountered in histopathology and cytology practice, where they can present as either benign mimickers of malignancy or true malignancies. The aim of this review is to provide a timely synthesis of our understanding of these tissue pathogens, with an emphasis on pertinent diagnostic conundrums associated with the benign mimickers of malignancy that can be seen with viral infections and those which manifest as granulomas. The oncogenic pathogens, including viruses, bacteria, and parasites, are then discussed with relationship to their associated malignancies. Although not exhaustive, the epidemiology, clinical manifestations, pathogenesis, and histological findings are included, along with a short review of emerging therapies. MDPI 2021-10-30 /pmc/articles/PMC8624235/ /pubmed/34832566 http://dx.doi.org/10.3390/pathogens10111410 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chua, Tzy Harn
Punjabi, Lavisha S
Khor, Li Yan
Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
title Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
title_full Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
title_fullStr Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
title_full_unstemmed Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
title_short Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
title_sort tissue pathogens and cancers: a review of commonly seen manifestations in histo- and cytopathology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624235/
https://www.ncbi.nlm.nih.gov/pubmed/34832566
http://dx.doi.org/10.3390/pathogens10111410
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