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Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology
Tissue pathogens are commonly encountered in histopathology and cytology practice, where they can present as either benign mimickers of malignancy or true malignancies. The aim of this review is to provide a timely synthesis of our understanding of these tissue pathogens, with an emphasis on pertine...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624235/ https://www.ncbi.nlm.nih.gov/pubmed/34832566 http://dx.doi.org/10.3390/pathogens10111410 |
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author | Chua, Tzy Harn Punjabi, Lavisha S Khor, Li Yan |
author_facet | Chua, Tzy Harn Punjabi, Lavisha S Khor, Li Yan |
author_sort | Chua, Tzy Harn |
collection | PubMed |
description | Tissue pathogens are commonly encountered in histopathology and cytology practice, where they can present as either benign mimickers of malignancy or true malignancies. The aim of this review is to provide a timely synthesis of our understanding of these tissue pathogens, with an emphasis on pertinent diagnostic conundrums associated with the benign mimickers of malignancy that can be seen with viral infections and those which manifest as granulomas. The oncogenic pathogens, including viruses, bacteria, and parasites, are then discussed with relationship to their associated malignancies. Although not exhaustive, the epidemiology, clinical manifestations, pathogenesis, and histological findings are included, along with a short review of emerging therapies. |
format | Online Article Text |
id | pubmed-8624235 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86242352021-11-27 Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology Chua, Tzy Harn Punjabi, Lavisha S Khor, Li Yan Pathogens Review Tissue pathogens are commonly encountered in histopathology and cytology practice, where they can present as either benign mimickers of malignancy or true malignancies. The aim of this review is to provide a timely synthesis of our understanding of these tissue pathogens, with an emphasis on pertinent diagnostic conundrums associated with the benign mimickers of malignancy that can be seen with viral infections and those which manifest as granulomas. The oncogenic pathogens, including viruses, bacteria, and parasites, are then discussed with relationship to their associated malignancies. Although not exhaustive, the epidemiology, clinical manifestations, pathogenesis, and histological findings are included, along with a short review of emerging therapies. MDPI 2021-10-30 /pmc/articles/PMC8624235/ /pubmed/34832566 http://dx.doi.org/10.3390/pathogens10111410 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chua, Tzy Harn Punjabi, Lavisha S Khor, Li Yan Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology |
title | Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology |
title_full | Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology |
title_fullStr | Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology |
title_full_unstemmed | Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology |
title_short | Tissue Pathogens and Cancers: A Review of Commonly Seen Manifestations in Histo- and Cytopathology |
title_sort | tissue pathogens and cancers: a review of commonly seen manifestations in histo- and cytopathology |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624235/ https://www.ncbi.nlm.nih.gov/pubmed/34832566 http://dx.doi.org/10.3390/pathogens10111410 |
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