Cargando…

RIG-I Deficiency Promotes Obesity-Induced Insulin Resistance

Inflammation and immunity are linked to the onset and development of obesity and metabolic disorders. Pattern recognition receptors (PRRs) are key regulators of inflammation and immunity in response to infection and stress, and they have critical roles in metainflammation. In this study, we investig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Gabsik, Lee, Hye Eun, Seok, Jin Kyung, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Lee, Joo Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624253/ https://www.ncbi.nlm.nih.gov/pubmed/34832960 http://dx.doi.org/10.3390/ph14111178

Ejemplares similares

Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis
por: Yang, Gabsik, et al.
Publicado: (2020)

Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells
por: Lee, Hye Eun, et al.
Publicado: (2019)

Loganin Prevents Hepatic Steatosis by Blocking NLRP3 Inflammasome Activation
por: Jang, Joo Hyeon, et al.
Publicado: (2023)

Inflammasomes and their roles in arthritic disease pathogenesis
por: Yang, Gabsik, et al.
Publicado: (2022)

Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis
por: Lee, Hye Eun, et al.
Publicado: (2019)

Oxidized Phospholipids in Tumor Microenvironment Stimulate Tumor Metastasis via Regulation of Autophagy
por: Seok, Jin Kyung, et al.
Publicado: (2021)

Loganin Alleviates Gout Inflammation by Suppressing NLRP3 Inflammasome Activation and Mitochondrial Damage
por: Choi, Nuri, et al.
Publicado: (2021)

Erratum: A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
por: Yang, Gabsik, et al.
Publicado: (2016)

A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
por: Yang, Gabsik, et al.
Publicado: (2016)

Structural features of influenza A virus panhandle RNA enabling the activation of RIG-I independently of 5′-triphosphate
por: Lee, Mi-Kyung, et al.
Publicado: (2016)

Recovery of TRIM25-Mediated RIG-I Ubiquitination through Suppression of NS1 by RNA Aptamers
por: Woo, Hye-Min, et al.
Publicado: (2019)

Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome
por: Yang, Gabsik, et al.
Publicado: (2020)

Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases
por: Seok, Jin Kyung, et al.
Publicado: (2021)

Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small Molecules
por: Seok, Jin Kyung, et al.
Publicado: (2021)

Suppression of Primary Splenocyte Proliferation by Artemisia capillaris and Its Components
por: Lee, Hye Eun, et al.
Publicado: (2017)

Sweroside Prevents Non-Alcoholic Steatohepatitis by Suppressing Activation of the NLRP3 Inflammasome
por: Yang, Gabsik, et al.
Publicado: (2020)

Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies
por: Lee, Janghyun, et al.
Publicado: (2018)

Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies
por: Lee, Janghyun, et al.
Publicado: (2018)

Beyond DNA sensing: expanding the role of cGAS/STING in immunity and diseases
por: Seok, Jin Kyung, et al.
Publicado: (2023)

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization
por: Wang, Wenshuai, et al.
Publicado: (2023)

Phloxine O, a Cosmetic Colorant, Suppresses the Expression of Thymic Stromal Lymphopoietin and Acute Dermatitis Symptoms in Mice
por: Lee, Hye Eun, et al.
Publicado: (2018)

Human Respiratory Syncytial Virus NS 1 Targets TRIM25 to Suppress RIG-I Ubiquitination and Subsequent RIG-I-Mediated Antiviral Signaling
por: Ban, Junsu, et al.
Publicado: (2018)

Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform
por: Nguyen, Nhung T.H., et al.
Publicado: (2016)

5′-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity
por: Hwang, Sun-Young, et al.
Publicado: (2012)

Targeting RIG-I or STING promotes epithelial regeneration
por: Fischer, Julius C., et al.
Publicado: (2017)

Stat2 stability regulation: an intersection between immunity and carcinogenesis
por: Lee, Cheol-Jung, et al.
Publicado: (2020)

Mitochondrial-Targeting Anticancer Agent Conjugates and Nanocarrier Systems for Cancer Treatment
por: Battogtokh, Gantumur, et al.
Publicado: (2018)

Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling
por: Guo, Guijie, et al.
Publicado: (2021)

SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization
por: Lee, Jae-Ho, et al.
Publicado: (2022)

Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5
por: Brisse, Morgan, et al.
Publicado: (2019)

Use of PCR with Sequence-specific Primers for High-Resolution Human Leukocyte Antigen Typing of Patients with Narcolepsy
por: Woo, Hye In, et al.
Publicado: (2012)

F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2
por: Lee, Cheol-Jung, et al.
Publicado: (2021)

Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling
por: Song, Jia, et al.
Publicado: (2022)

Tetrahydrofurofuranoid Lignans, Eudesmin, Fargesin, Epimagnolin A, Magnolin, and Yangambin Inhibit UDP-Glucuronosyltransferase 1A1 and 1A3 Activities in Human Liver Microsomes
por: Park, Ria, et al.
Publicado: (2021)

CCR2 knockout ameliorates obesity-induced kidney injury through inhibiting oxidative stress and ER stress
por: Lee, Seung Joo, et al.
Publicado: (2019)

Enhanced ANGPTL2 expression in adipose tissues and its association with insulin resistance in obese women
por: Kim, Jimin, et al.
Publicado: (2018)

TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling
por: Lee, Hwan Hee, et al.
Publicado: (2022)

Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout
por: Lee, Hye Eun, et al.
Publicado: (2016)

PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD–RIG-I–NF-κB axis
por: Kim, Hyun-Kyoung, et al.
Publicado: (2018)

Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response
por: Kouwaki, Takahisa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4bn4tdilj2pcomorfqs9jeu4ak