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Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts

This review presents materials characterizing sulfated polysaccharides (SPS) of marine hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of protozoa and helminthiasis. The authors have summarized the literature on the pathogenetic targets of protozoa on the ho...

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Autores principales: Besednova, Natalya N., Zaporozhets, Tatyana S., Andryukov, Boris G., Kryzhanovsky, Sergey P., Ermakova, Svetlana P., Kuznetsova, Tatyana A., Voronova, Anastasia N., Shchelkanov, Mikhail Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624348/
https://www.ncbi.nlm.nih.gov/pubmed/34822508
http://dx.doi.org/10.3390/md19110637
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author Besednova, Natalya N.
Zaporozhets, Tatyana S.
Andryukov, Boris G.
Kryzhanovsky, Sergey P.
Ermakova, Svetlana P.
Kuznetsova, Tatyana A.
Voronova, Anastasia N.
Shchelkanov, Mikhail Y.
author_facet Besednova, Natalya N.
Zaporozhets, Tatyana S.
Andryukov, Boris G.
Kryzhanovsky, Sergey P.
Ermakova, Svetlana P.
Kuznetsova, Tatyana A.
Voronova, Anastasia N.
Shchelkanov, Mikhail Y.
author_sort Besednova, Natalya N.
collection PubMed
description This review presents materials characterizing sulfated polysaccharides (SPS) of marine hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of protozoa and helminthiasis. The authors have summarized the literature on the pathogenetic targets of protozoa on the host cells and on the antiparasitic potential of polysaccharides from red, brown and green algae as well as certain marine invertebrates. Information about the mechanisms of action of these unique compounds in diseases caused by protozoa has also been summarized. SPS is distinguished by high antiparasitic activity, good solubility and an almost complete absence of toxicity. In the long term, this allows for the consideration of these compounds as effective and attractive candidates on which to base drugs, biologically active food additives and functional food products with antiparasitic activity.
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spelling pubmed-86243482021-11-27 Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts Besednova, Natalya N. Zaporozhets, Tatyana S. Andryukov, Boris G. Kryzhanovsky, Sergey P. Ermakova, Svetlana P. Kuznetsova, Tatyana A. Voronova, Anastasia N. Shchelkanov, Mikhail Y. Mar Drugs Review This review presents materials characterizing sulfated polysaccharides (SPS) of marine hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of protozoa and helminthiasis. The authors have summarized the literature on the pathogenetic targets of protozoa on the host cells and on the antiparasitic potential of polysaccharides from red, brown and green algae as well as certain marine invertebrates. Information about the mechanisms of action of these unique compounds in diseases caused by protozoa has also been summarized. SPS is distinguished by high antiparasitic activity, good solubility and an almost complete absence of toxicity. In the long term, this allows for the consideration of these compounds as effective and attractive candidates on which to base drugs, biologically active food additives and functional food products with antiparasitic activity. MDPI 2021-11-12 /pmc/articles/PMC8624348/ /pubmed/34822508 http://dx.doi.org/10.3390/md19110637 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Besednova, Natalya N.
Zaporozhets, Tatyana S.
Andryukov, Boris G.
Kryzhanovsky, Sergey P.
Ermakova, Svetlana P.
Kuznetsova, Tatyana A.
Voronova, Anastasia N.
Shchelkanov, Mikhail Y.
Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts
title Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts
title_full Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts
title_fullStr Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts
title_full_unstemmed Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts
title_short Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts
title_sort antiparasitic effects of sulfated polysaccharides from marine hydrobionts
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624348/
https://www.ncbi.nlm.nih.gov/pubmed/34822508
http://dx.doi.org/10.3390/md19110637
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