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Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update
Melanoma is an aggressive skin cancer, whose incidence rates have increased over the past few decades. Risk factors for melanoma are both intrinsic (genetic and familiar predisposition) and extrinsic (environment, including sun exposure, and lifestyle). The recent advent of targeted and immune-based...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624488/ https://www.ncbi.nlm.nih.gov/pubmed/34836273 http://dx.doi.org/10.3390/nu13114018 |
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author | Pellegrini, Marianna D’Eusebio, Chiara Ponzo, Valentina Tonella, Luca Finocchiaro, Concetta Fierro, Maria Teresa Quaglino, Pietro Bo, Simona |
author_facet | Pellegrini, Marianna D’Eusebio, Chiara Ponzo, Valentina Tonella, Luca Finocchiaro, Concetta Fierro, Maria Teresa Quaglino, Pietro Bo, Simona |
author_sort | Pellegrini, Marianna |
collection | PubMed |
description | Melanoma is an aggressive skin cancer, whose incidence rates have increased over the past few decades. Risk factors for melanoma are both intrinsic (genetic and familiar predisposition) and extrinsic (environment, including sun exposure, and lifestyle). The recent advent of targeted and immune-based therapies has revolutionized the treatment of melanoma, and research is focusing on strategies to optimize them. Obesity is an established risk factor for several cancer types, but its possible role in the etiology of melanoma is controversial. Body mass index, body surface area, and height have been related to the risk for cutaneous melanoma, although an ‘obesity paradox’ has been described too. Increasing evidence suggests the role of nutritional factors in the prevention and management of melanoma. Several studies have demonstrated the impact of dietary attitudes, specific foods, and nutrients both on the risk for melanoma and on the progression of the disease, via the effects on the oncological treatments. The aim of this narrative review was to summarize the main literature results regarding the preventive and therapeutic role of nutritional schemes, specific foods, and nutrients on melanoma incidence and progression. |
format | Online Article Text |
id | pubmed-8624488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86244882021-11-27 Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update Pellegrini, Marianna D’Eusebio, Chiara Ponzo, Valentina Tonella, Luca Finocchiaro, Concetta Fierro, Maria Teresa Quaglino, Pietro Bo, Simona Nutrients Review Melanoma is an aggressive skin cancer, whose incidence rates have increased over the past few decades. Risk factors for melanoma are both intrinsic (genetic and familiar predisposition) and extrinsic (environment, including sun exposure, and lifestyle). The recent advent of targeted and immune-based therapies has revolutionized the treatment of melanoma, and research is focusing on strategies to optimize them. Obesity is an established risk factor for several cancer types, but its possible role in the etiology of melanoma is controversial. Body mass index, body surface area, and height have been related to the risk for cutaneous melanoma, although an ‘obesity paradox’ has been described too. Increasing evidence suggests the role of nutritional factors in the prevention and management of melanoma. Several studies have demonstrated the impact of dietary attitudes, specific foods, and nutrients both on the risk for melanoma and on the progression of the disease, via the effects on the oncological treatments. The aim of this narrative review was to summarize the main literature results regarding the preventive and therapeutic role of nutritional schemes, specific foods, and nutrients on melanoma incidence and progression. MDPI 2021-11-11 /pmc/articles/PMC8624488/ /pubmed/34836273 http://dx.doi.org/10.3390/nu13114018 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pellegrini, Marianna D’Eusebio, Chiara Ponzo, Valentina Tonella, Luca Finocchiaro, Concetta Fierro, Maria Teresa Quaglino, Pietro Bo, Simona Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update |
title | Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update |
title_full | Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update |
title_fullStr | Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update |
title_full_unstemmed | Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update |
title_short | Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update |
title_sort | nutritional interventions for patients with melanoma: from prevention to therapy—an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624488/ https://www.ncbi.nlm.nih.gov/pubmed/34836273 http://dx.doi.org/10.3390/nu13114018 |
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