Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing’s Sarcoma, Enhancing T Cell Cytotoxicity

Ewing’s sarcoma (EwS) is a pediatric solid tumor entity with low somatic mutational burden and a low rate of tumor-infiltrating T cells, indicating a low extent of immunogenicity. In EwS, immunogenicity may furthermore be significantly diminished by a predominantly M2 macrophage driven pro-tumorigen...

Descripción completa

Detalles Bibliográficos
Autores principales: Biele, Emilie, Schober, Sebastian J., Prexler, Carolin, Thiede, Melanie, von Heyking, Kristina, Gassmann, Hendrik, Eck, Jennifer, Xue, Busheng, Burdach, Stefan, Thiel, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624504/
https://www.ncbi.nlm.nih.gov/pubmed/34831294
http://dx.doi.org/10.3390/cells10113070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624504/
https://www.ncbi.nlm.nih.gov/pubmed/34831294
http://dx.doi.org/10.3390/cells10113070

Ejemplares similares