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Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing’s Sarcoma, Enhancing T Cell Cytotoxicity

Ewing’s sarcoma (EwS) is a pediatric solid tumor entity with low somatic mutational burden and a low rate of tumor-infiltrating T cells, indicating a low extent of immunogenicity. In EwS, immunogenicity may furthermore be significantly diminished by a predominantly M2 macrophage driven pro-tumorigen...

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Detalles Bibliográficos
Autores principales:	Biele, Emilie, Schober, Sebastian J., Prexler, Carolin, Thiede, Melanie, von Heyking, Kristina, Gassmann, Hendrik, Eck, Jennifer, Xue, Busheng, Burdach, Stefan, Thiel, Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624504/ https://www.ncbi.nlm.nih.gov/pubmed/34831294 http://dx.doi.org/10.3390/cells10113070

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