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Monoclonal Human Antibodies That Recognise the Exposed N and C Terminal Regions of the Often-Overlooked SARS-CoV-2 ORF3a Transmembrane Protein

ORF3a has been identified as a viroporin of SARS-CoV-2 and is known to be involved in various pathophysiological activities including disturbance of cellular calcium homeostasis, inflammasome activation, apoptosis induction and disruption of autophagy. ORF3a-targeting antibodies may specifically and...

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Detalles Bibliográficos
Autores principales:	Tan, Tyng Hwey, Patton, Elizabeth, Munro, Carol A., Corzo-Leon, Dora E., Porter, Andrew J., Palliyil, Soumya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624585/ https://www.ncbi.nlm.nih.gov/pubmed/34835009 http://dx.doi.org/10.3390/v13112201

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