Acetylenic Synthetic Betulin Derivatives Inhibit Akt and Erk Kinases Activity, Trigger Apoptosis and Suppress Proliferation of Neuroblastoma and Rhabdomyosarcoma Cell Lines

Neuroblastoma (NB) and rhabdomyosarcoma (RMS), the most common pediatric extracranial solid tumors, still represent an important clinical challenge since no effective treatment is available for metastatic and recurrent disease. Hence, there is an urgent need for the development of new chemotherapeut...

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Detalles Bibliográficos
Autores principales: Król, Sylwia K., Bębenek, Ewa, Dmoszyńska-Graniczka, Magdalena, Sławińska-Brych, Adrianna, Boryczka, Stanisław, Stepulak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624615/
https://www.ncbi.nlm.nih.gov/pubmed/34830180
http://dx.doi.org/10.3390/ijms222212299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624615/
https://www.ncbi.nlm.nih.gov/pubmed/34830180
http://dx.doi.org/10.3390/ijms222212299

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