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PI3K/AKT/mTOR Signaling Pathway Is Required for JCPyV Infection in Primary Astrocytes

Astrocytes are a main target of JC polyomavirus (JCPyV) in the central nervous system (CNS), where the destruction of these cells, along with oligodendrocytes, leads to the fatal disease progressive multifocal leukoencephalopathy (PML). There is no cure currently available for PML, so it is essentia...

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Detalles Bibliográficos
Autores principales:	Wilczek, Michael P., Armstrong, Francesca J., Mayberry, Colleen L., King, Benjamin L., Maginnis, Melissa S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624856/ https://www.ncbi.nlm.nih.gov/pubmed/34831441 http://dx.doi.org/10.3390/cells10113218

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