Cargando…

Insights into the SARS-CoV-2-Mediated Alteration in the Stress Granule Protein Regulatory Networks in Humans

The rapidly and constantly evolving coronavirus, SARS-CoV-2, imposes a great threat to human health causing severe lung disease and significant mortality. Cytoplasmic stress granules (SGs) exert anti-viral activities due to their involvement in translation inhibition and innate immune signaling. SAR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prasad, Kartikay, Alasmari, Abdullah F., Ali, Nemat, Khan, Rehan, Alghamdi, Adel, Kumar, Vijay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624858/ https://www.ncbi.nlm.nih.gov/pubmed/34832615 http://dx.doi.org/10.3390/pathogens10111459

Ejemplares similares

Genomics-guided targeting of stress granule proteins G3BP1/2 to inhibit SARS-CoV-2 propagation
por: Ali, Nemat, et al.
Publicado: (2021)

In silico investigations of heparin binding to SARS‐CoV‐2 variants with a focus at the RBD/ACE2 interface
por: Ali, Nemat, et al.
Publicado: (2022)

Artificial intelligence-driven drug repurposing and structural biology for SARS-CoV-2
por: Prasad, Kartikay, et al.
Publicado: (2021)

Insights into the biased activity of dextromethorphan and haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis
por: Pandey, Preeti, et al.
Publicado: (2020)

Targeting hub genes and pathways of innate immune response in COVID-19: A network biology perspective
por: Prasad, Kartikay, et al.
Publicado: (2020)

The SARS-CoV-2 targeted human RNA binding proteins network biology to investigate COVID-19 associated manifestations
por: Prasad, Kartikay, et al.
Publicado: (2022)

Genomics-guided identification of potential modulators of SARS-CoV-2 entry proteases, TMPRSS2 and Cathepsins B/L
por: Prasad, Kartikay, et al.
Publicado: (2021)

In silico identification of MicroRNAs targeting the key nucleator of stress granules, G3BP: Promising therapeutics for SARS-CoV-2 infection
por: Almutairy, Bjad K., et al.
Publicado: (2021)

Targeting DNA methylation can reduce cardiac injury associated with ischemia reperfusion: One step closer to clinical translation with blood-borne assessment
por: Boovarahan, Sri Rahavi, et al.
Publicado: (2022)

Investigating Chaperone like Activity of Green Silver Nanoparticles: Possible Implications in Drug Development
por: Rauf, Mohd Ahmar, et al.
Publicado: (2022)

Venetoclax Induces Cardiotoxicity through Modulation of Oxidative-Stress-Mediated Cardiac Inflammation and Apoptosis via NF-κB and BCL-2 Pathway
por: AlAsmari, Abdullah F., et al.
Publicado: (2022)

SARS-CoV-2 mutations altering regulatory properties: Deciphering host's and virus's perspectives
por: Islam, Abul Bashar Mir Md. Khademul, et al.
Publicado: (2021)

Age-associated global DNA hypermethylation augments the sensitivity of hearts towards ischemia-reperfusion injury
por: Boovarahan, Sri Rahavi, et al.
Publicado: (2022)

Neurological manifestations of COVID-19: available evidences and a new paradigm
por: Khatoon, Fatima, et al.
Publicado: (2020)

COVID-19 associated nervous system manifestations
por: Khatoon, Fatima, et al.
Publicado: (2022)

Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study
por: AlAsmari, Abdullah F., et al.
Publicado: (2021)

Mechanistic insights into mammalian stress granule dynamics
por: Panas, Marc D., et al.
Publicado: (2016)

Targeting cathepsins: A potential link between COVID-19 and associated neurological manifestations
por: Prasad, Kartikay, et al.
Publicado: (2021)

A New Phase of Networking: The Molecular Composition and Regulatory Dynamics of Mammalian Stress Granules
por: Millar, Sean R., et al.
Publicado: (2023)

SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation
por: Li, Yichen, et al.
Publicado: (2022)

SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication
por: Zheng, Zhou-Qin, et al.
Publicado: (2021)

Brain Disease Network Analysis to Elucidate the Neurological Manifestations of COVID-19
por: Prasad, Kartikay, et al.
Publicado: (2021)

Plant RNA Regulatory Network and RNA Granules in Virus Infection
por: Mäkinen, Kristiina, et al.
Publicado: (2017)

The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition
por: Martin, Jack L., et al.
Publicado: (2023)

Mutations in SARS-CoV-2 ORF8 Altered the Bonding Network With Interferon Regulatory Factor 3 to Evade Host Immune System
por: Rashid, Farooq, et al.
Publicado: (2021)

Differential effect of SARS-CoV-2 infection on stress granule formation in Vero and Calu-3 cells
por: Kim, Dongbum, et al.
Publicado: (2022)

Diabetic Hearts Exhibit Global DNA Hypermethylation That Alter the Mitochondrial Functional Genes to Enhance the Sensitivity of the Heart to Ischemia Reperfusion Injury
por: Boovarahan, Sri Rahavi, et al.
Publicado: (2022)

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
por: Nabeel-Shah, Syed, et al.
Publicado: (2021)

Geraniol Ameliorates Doxorubicin-Mediated Kidney Injury through Alteration of Antioxidant Status, Inflammation, and Apoptosis: Potential Roles of NF-κB and Nrf2/Ho-1
por: AlAsmari, Abdullah F., et al.
Publicado: (2022)

SARS‐CoV‐2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets
por: Somasekharan, Syam Prakash, et al.
Publicado: (2021)

Triethylammonium salt of a synthesized dicoumarol: Structural insight and human anti-glioblastoma activities
por: Khan, Afzal, et al.
Publicado: (2023)

Pooled CRISPR screens with imaging on microRaft arrays reveals stress granule-regulatory factors
por: Wheeler, Emily C., et al.
Publicado: (2020)

Stress granules regulate paraspeckles: RNP granule continuum at work
por: An, Haiyan, et al.
Publicado: (2019)

Identification and Characterization of the Heat-Induced Plastidial Stress Granules Reveal New Insight Into Arabidopsis Stress Response
por: Chodasiewicz, Monika, et al.
Publicado: (2020)

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics
por: Baron, Desiree M, et al.
Publicado: (2013)

Molecular Insights into SARS-CoV2-Induced Alterations of the Gut/Brain Axis
por: Nataf, Serge, et al.
Publicado: (2021)

Consequential Impact of Particulate Matter Linked Inter-Fibrillar Mitochondrial Dysfunction in Rat Myocardium Subjected to Ischemia Reperfusion Injury
por: Sivakumar, Bhavana, et al.
Publicado: (2022)

Viral modulation of stress granules
por: Valiente-Echeverría, Fernando, et al.
Publicado: (2012)

Editorial: The Dynamics of Stress Granules
por: Mehto, Subhash, et al.
Publicado: (2021)

Biomolecular phase separation in stress granule assembly and virus infection: Stress granule and virus infection
por: Liu, Yi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e424d7lvl8v3dt7nhmj2u15ofb