Upregulated Guanine Deaminase Is Involved in Hyperpigmentation of Seborrheic Keratosis via Uric Acid Release

Seborrheic keratosis, which is a benign tumor composed of epidermal keratinocytes, develops common in the elderly. Uric acid generated by upregulated guanine deaminase (GDA) has been identified to cause UV-induced keratinocyte senescence in seborrheic keratosis. Seborrheic keratosis is also frequent...

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Detalles Bibliográficos
Autores principales: Cheong, Kyung Ah, Kil, In Sup, Ko, Hyuk Wan, Lee, Ai-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625227/
https://www.ncbi.nlm.nih.gov/pubmed/34830382
http://dx.doi.org/10.3390/ijms222212501

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