Cargando…

Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia

The impact of body composition on the early origin of chronic diseases is an increasingly appreciated phenomenon. Little is known about the characteristics of children with varying body composition. The aim of this study was to investigate serum lipid profiles and other characteristics in relation t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ofenheimer, Alina, Breyer-Kohansal, Robab, Hartl, Sylvia, Burghuber, Otto C., Krach, Florian, Franssen, Frits M. E., Wouters, Emiel F. M., Breyer, Marie-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625256/
https://www.ncbi.nlm.nih.gov/pubmed/34828760
http://dx.doi.org/10.3390/children8111047
_version_ 1784606375412760576
author Ofenheimer, Alina
Breyer-Kohansal, Robab
Hartl, Sylvia
Burghuber, Otto C.
Krach, Florian
Franssen, Frits M. E.
Wouters, Emiel F. M.
Breyer, Marie-Kathrin
author_facet Ofenheimer, Alina
Breyer-Kohansal, Robab
Hartl, Sylvia
Burghuber, Otto C.
Krach, Florian
Franssen, Frits M. E.
Wouters, Emiel F. M.
Breyer, Marie-Kathrin
author_sort Ofenheimer, Alina
collection PubMed
description The impact of body composition on the early origin of chronic diseases is an increasingly appreciated phenomenon. Little is known about the characteristics of children with varying body composition. The aim of this study was to investigate serum lipid profiles and other characteristics in relation to body composition. The data of 1394 participants (aged 6 to <18 years) of the observational general population-based Austrian LEAD Study have been analyzed. Body composition groups were defined by appendicular lean mass (ALMI) and fat mass (FMI) indices assessed by DXA. Serum lipid profiles (triglycerides, LDL-c, HDL-c) and other characteristics (e.g., prematurity, smoke exposure, physical activity, nutrition) were investigated in these body composition groups. Different body composition groups, which are not distinguishable by BMI, exist. Children with high ALMI and high FMI showed higher triglycerides and LDL-c, but lower HDL-c levels. In contrast, levels did not differ between those with high FMI but low (or normal) ALMI, and other body composition groups. BMI should be interpreted cautiously, and body composition should be measured by more precise techniques. In particular, children and adolescents with high FMI who have concomitantly high ALMI should be followed closely in future studies to investigate whether they are at increased risk of cardiovascular problems.
format Online
Article
Text
id pubmed-8625256
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86252562021-11-27 Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia Ofenheimer, Alina Breyer-Kohansal, Robab Hartl, Sylvia Burghuber, Otto C. Krach, Florian Franssen, Frits M. E. Wouters, Emiel F. M. Breyer, Marie-Kathrin Children (Basel) Article The impact of body composition on the early origin of chronic diseases is an increasingly appreciated phenomenon. Little is known about the characteristics of children with varying body composition. The aim of this study was to investigate serum lipid profiles and other characteristics in relation to body composition. The data of 1394 participants (aged 6 to <18 years) of the observational general population-based Austrian LEAD Study have been analyzed. Body composition groups were defined by appendicular lean mass (ALMI) and fat mass (FMI) indices assessed by DXA. Serum lipid profiles (triglycerides, LDL-c, HDL-c) and other characteristics (e.g., prematurity, smoke exposure, physical activity, nutrition) were investigated in these body composition groups. Different body composition groups, which are not distinguishable by BMI, exist. Children with high ALMI and high FMI showed higher triglycerides and LDL-c, but lower HDL-c levels. In contrast, levels did not differ between those with high FMI but low (or normal) ALMI, and other body composition groups. BMI should be interpreted cautiously, and body composition should be measured by more precise techniques. In particular, children and adolescents with high FMI who have concomitantly high ALMI should be followed closely in future studies to investigate whether they are at increased risk of cardiovascular problems. MDPI 2021-11-13 /pmc/articles/PMC8625256/ /pubmed/34828760 http://dx.doi.org/10.3390/children8111047 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ofenheimer, Alina
Breyer-Kohansal, Robab
Hartl, Sylvia
Burghuber, Otto C.
Krach, Florian
Franssen, Frits M. E.
Wouters, Emiel F. M.
Breyer, Marie-Kathrin
Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia
title Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia
title_full Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia
title_fullStr Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia
title_full_unstemmed Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia
title_short Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia
title_sort using body composition groups to identify children and adolescents at risk of dyslipidemia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625256/
https://www.ncbi.nlm.nih.gov/pubmed/34828760
http://dx.doi.org/10.3390/children8111047
work_keys_str_mv AT ofenheimeralina usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT breyerkohansalrobab usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT hartlsylvia usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT burghuberottoc usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT krachflorian usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT franssenfritsme usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT woutersemielfm usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia
AT breyermariekathrin usingbodycompositiongroupstoidentifychildrenandadolescentsatriskofdyslipidemia