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Rational Design of Simple Organocatalysts for the HSiCl(3) Enantioselective Reduction of (E)-N-(1-Phenylethylidene)aniline

Prolinamides are well-known organocatalysts for the HSiCl(3) reduction of imines; however, custom design of catalysts is based on trial-and-error experiments. In this work, we have used a combination of computational calculations and experimental work, including kinetic analyses, to properly underst...

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Detalles Bibliográficos
Autores principales: Maciá, María, Porcar, Raúl, Martí-Centelles, Vicente, García-Verdugo, Eduardo, Burguete, Maria Isabel, Luis, Santiago V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625272/
https://www.ncbi.nlm.nih.gov/pubmed/34834055
http://dx.doi.org/10.3390/molecules26226963

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