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Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignoranc...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625318/ https://www.ncbi.nlm.nih.gov/pubmed/34828287 http://dx.doi.org/10.3390/genes12111682 |
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author | Balberova, Olga V. Bykov, Evgeny V. Medvedev, German V. Zhogina, Margarita A. Petrov, Kirill V. Petrova, Marina M. Al-Zamil, Mustafa Trefilova, Vera V. Goncharova, Polina S. Shnayder, Natalia A. |
author_facet | Balberova, Olga V. Bykov, Evgeny V. Medvedev, German V. Zhogina, Margarita A. Petrov, Kirill V. Petrova, Marina M. Al-Zamil, Mustafa Trefilova, Vera V. Goncharova, Polina S. Shnayder, Natalia A. |
author_sort | Balberova, Olga V. |
collection | PubMed |
description | All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignorance of these features can create genetic “barriers” that prevent professional athletes from pursuing a career in sports. Predictive Genomic DNA Profiling reveals single nucleotide variations (SNV) that may be associated with better suitability for endurance, strength and speed sports. (1) Background: To conduct a research on candidate genes associated with regulation of skeletal muscle energy metabolism among athletes. (2) Methods: We have searched for articles in SCOPUS, Web of Science, Google Scholar, Clinical keys, PubMed, e-LIBRARY databases for the period of 2010–2020 using keywords and keywords combinations; (4) Conclusions: Identification of genetic markers associated with the regulation of energy metabolism in skeletal muscles can help sports physicians and coaches develop personalized strategies for selecting children, teenagers and young adults for endurance, strength and speed sports (such as jogging, middle or long distance runs). However, the multifactorial aspect of sport performances, including impact of genetics, epigenetics, environment (training and etc.), is important for personalized strategies for selecting of athletes. This approach could improve sports performance and reduce the risk of sports injuries to the musculoskeletal system. |
format | Online Article Text |
id | pubmed-8625318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86253182021-11-27 Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes Balberova, Olga V. Bykov, Evgeny V. Medvedev, German V. Zhogina, Margarita A. Petrov, Kirill V. Petrova, Marina M. Al-Zamil, Mustafa Trefilova, Vera V. Goncharova, Polina S. Shnayder, Natalia A. Genes (Basel) Review All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignorance of these features can create genetic “barriers” that prevent professional athletes from pursuing a career in sports. Predictive Genomic DNA Profiling reveals single nucleotide variations (SNV) that may be associated with better suitability for endurance, strength and speed sports. (1) Background: To conduct a research on candidate genes associated with regulation of skeletal muscle energy metabolism among athletes. (2) Methods: We have searched for articles in SCOPUS, Web of Science, Google Scholar, Clinical keys, PubMed, e-LIBRARY databases for the period of 2010–2020 using keywords and keywords combinations; (4) Conclusions: Identification of genetic markers associated with the regulation of energy metabolism in skeletal muscles can help sports physicians and coaches develop personalized strategies for selecting children, teenagers and young adults for endurance, strength and speed sports (such as jogging, middle or long distance runs). However, the multifactorial aspect of sport performances, including impact of genetics, epigenetics, environment (training and etc.), is important for personalized strategies for selecting of athletes. This approach could improve sports performance and reduce the risk of sports injuries to the musculoskeletal system. MDPI 2021-10-23 /pmc/articles/PMC8625318/ /pubmed/34828287 http://dx.doi.org/10.3390/genes12111682 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Balberova, Olga V. Bykov, Evgeny V. Medvedev, German V. Zhogina, Margarita A. Petrov, Kirill V. Petrova, Marina M. Al-Zamil, Mustafa Trefilova, Vera V. Goncharova, Polina S. Shnayder, Natalia A. Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes |
title | Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes |
title_full | Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes |
title_fullStr | Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes |
title_full_unstemmed | Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes |
title_short | Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes |
title_sort | candidate genes of regulation of skeletal muscle energy metabolism in athletes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625318/ https://www.ncbi.nlm.nih.gov/pubmed/34828287 http://dx.doi.org/10.3390/genes12111682 |
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