Transfer of Cellular Content from the Allogeneic Cell-Based Cancer Vaccine DCP-001 to Host Dendritic Cells Hinges on Phosphatidylserine and Is Enhanced by CD47 Blockade

DCP-001 is a cell-based cancer vaccine generated by differentiation and maturation of cells from the human DCOne myeloid leukemic cell line. This results in a vaccine comprising a broad array of endogenous tumor antigens combined with a mature dendritic cell (mDC) costimulatory profile, functioning...

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Detalles Bibliográficos
Autores principales: Zuo, Haoxiao, van Lierop, Marie-José C., Kaspers, Jorn, Bos, Remco, Reurs, Anneke, Sarkar, Saheli, Konry, Tania, Kamermans, Alwin, Kooij, Gijs, de Vries, Helga E., de Gruijl, Tanja D., Karlsson-Parra, Alex, Manting, Erik H., Kruisbeek, Ada M., Singh, Satwinder Kaur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625408/
https://www.ncbi.nlm.nih.gov/pubmed/34831455
http://dx.doi.org/10.3390/cells10113233

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