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Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration, particularly when a lack of osseointegration an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625459/ https://www.ncbi.nlm.nih.gov/pubmed/34835740 http://dx.doi.org/10.3390/nano11112977 |
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author | Vijay, Renjini Mendhi, Jayanti Prasad, Karthika Xiao, Yin MacLeod, Jennifer Ostrikov, Kostya (Ken) Zhou, Yinghong |
author_facet | Vijay, Renjini Mendhi, Jayanti Prasad, Karthika Xiao, Yin MacLeod, Jennifer Ostrikov, Kostya (Ken) Zhou, Yinghong |
author_sort | Vijay, Renjini |
collection | PubMed |
description | Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration, particularly when a lack of osseointegration and immunoregulatory incompetency occur during the healing phase, resulting in infection and fibrous encapsulation. Bio-inspired or biomimetic materials, which can mimic the characteristics of natural elements, are being investigated for use in the implant industry. This review discusses different biomimetic dental implants in terms of structural changes that enable antibacterial properties, drug delivery, immunomodulation, and osseointegration. We subsequently summarize the modification of dental implants for diabetes patients utilizing carbon nanomaterials, which have been recently found to improve the characteristics of biomimetic dental implants, including through antibacterial and anti-inflammatory capabilities, and by offering drug delivery properties that are essential for the success of dental implants. |
format | Online Article Text |
id | pubmed-8625459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86254592021-11-27 Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients Vijay, Renjini Mendhi, Jayanti Prasad, Karthika Xiao, Yin MacLeod, Jennifer Ostrikov, Kostya (Ken) Zhou, Yinghong Nanomaterials (Basel) Review Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration, particularly when a lack of osseointegration and immunoregulatory incompetency occur during the healing phase, resulting in infection and fibrous encapsulation. Bio-inspired or biomimetic materials, which can mimic the characteristics of natural elements, are being investigated for use in the implant industry. This review discusses different biomimetic dental implants in terms of structural changes that enable antibacterial properties, drug delivery, immunomodulation, and osseointegration. We subsequently summarize the modification of dental implants for diabetes patients utilizing carbon nanomaterials, which have been recently found to improve the characteristics of biomimetic dental implants, including through antibacterial and anti-inflammatory capabilities, and by offering drug delivery properties that are essential for the success of dental implants. MDPI 2021-11-05 /pmc/articles/PMC8625459/ /pubmed/34835740 http://dx.doi.org/10.3390/nano11112977 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Vijay, Renjini Mendhi, Jayanti Prasad, Karthika Xiao, Yin MacLeod, Jennifer Ostrikov, Kostya (Ken) Zhou, Yinghong Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients |
title | Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients |
title_full | Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients |
title_fullStr | Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients |
title_full_unstemmed | Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients |
title_short | Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients |
title_sort | carbon nanomaterials modified biomimetic dental implants for diabetic patients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625459/ https://www.ncbi.nlm.nih.gov/pubmed/34835740 http://dx.doi.org/10.3390/nano11112977 |
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