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Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients

Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration, particularly when a lack of osseointegration an...

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Autores principales: Vijay, Renjini, Mendhi, Jayanti, Prasad, Karthika, Xiao, Yin, MacLeod, Jennifer, Ostrikov, Kostya (Ken), Zhou, Yinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625459/
https://www.ncbi.nlm.nih.gov/pubmed/34835740
http://dx.doi.org/10.3390/nano11112977
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author Vijay, Renjini
Mendhi, Jayanti
Prasad, Karthika
Xiao, Yin
MacLeod, Jennifer
Ostrikov, Kostya (Ken)
Zhou, Yinghong
author_facet Vijay, Renjini
Mendhi, Jayanti
Prasad, Karthika
Xiao, Yin
MacLeod, Jennifer
Ostrikov, Kostya (Ken)
Zhou, Yinghong
author_sort Vijay, Renjini
collection PubMed
description Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration, particularly when a lack of osseointegration and immunoregulatory incompetency occur during the healing phase, resulting in infection and fibrous encapsulation. Bio-inspired or biomimetic materials, which can mimic the characteristics of natural elements, are being investigated for use in the implant industry. This review discusses different biomimetic dental implants in terms of structural changes that enable antibacterial properties, drug delivery, immunomodulation, and osseointegration. We subsequently summarize the modification of dental implants for diabetes patients utilizing carbon nanomaterials, which have been recently found to improve the characteristics of biomimetic dental implants, including through antibacterial and anti-inflammatory capabilities, and by offering drug delivery properties that are essential for the success of dental implants.
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spelling pubmed-86254592021-11-27 Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients Vijay, Renjini Mendhi, Jayanti Prasad, Karthika Xiao, Yin MacLeod, Jennifer Ostrikov, Kostya (Ken) Zhou, Yinghong Nanomaterials (Basel) Review Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration, particularly when a lack of osseointegration and immunoregulatory incompetency occur during the healing phase, resulting in infection and fibrous encapsulation. Bio-inspired or biomimetic materials, which can mimic the characteristics of natural elements, are being investigated for use in the implant industry. This review discusses different biomimetic dental implants in terms of structural changes that enable antibacterial properties, drug delivery, immunomodulation, and osseointegration. We subsequently summarize the modification of dental implants for diabetes patients utilizing carbon nanomaterials, which have been recently found to improve the characteristics of biomimetic dental implants, including through antibacterial and anti-inflammatory capabilities, and by offering drug delivery properties that are essential for the success of dental implants. MDPI 2021-11-05 /pmc/articles/PMC8625459/ /pubmed/34835740 http://dx.doi.org/10.3390/nano11112977 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vijay, Renjini
Mendhi, Jayanti
Prasad, Karthika
Xiao, Yin
MacLeod, Jennifer
Ostrikov, Kostya (Ken)
Zhou, Yinghong
Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
title Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
title_full Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
title_fullStr Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
title_full_unstemmed Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
title_short Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients
title_sort carbon nanomaterials modified biomimetic dental implants for diabetic patients
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625459/
https://www.ncbi.nlm.nih.gov/pubmed/34835740
http://dx.doi.org/10.3390/nano11112977
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