Intrabody Targeting HIF-1α Mediates Transcriptional Downregulation of Target Genes Related to Solid Tumors

Uncontrolled growth of solid tumors will result in a hallmark hypoxic condition, whereby the key transcriptional regulator of hypoxia inducible factor-1α (HIF-1α) will be stabilized to activate the transcription of target genes that are responsible for the metabolism, proliferation, and metastasis o...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yaozhong, Romão, Ema, Vincke, Cécile, Brys, Lea, Elkrim, Yvon, Vandevenne, Marylène, Liu, Changxiao, Muyldermans, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625554/
https://www.ncbi.nlm.nih.gov/pubmed/34830219
http://dx.doi.org/10.3390/ijms222212335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625554/
https://www.ncbi.nlm.nih.gov/pubmed/34830219
http://dx.doi.org/10.3390/ijms222212335

Ejemplares similares