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Use of an In Vitro Skin Parallel Artificial Membrane Assay (Skin-PAMPA) as a Screening Tool to Compare Transdermal Permeability of Model Compound 4-Phenylethyl-Resorcinol Dissolved in Different Solvents

Absorption through the skin of topically applied chemicals is relevant for both formulation development and safety assessment, especially in the early stages of development. However, the supply of human skin is limited, and the traditional in vitro methods are of low throughput. As an alternative, a...

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Detalles Bibliográficos
Autores principales: Sinkó, Bálint, Bárdos, Vivien, Vesztergombi, Dániel, Kádár, Szabina, Malcsiner, Petra, Moustie, Anne, Jouy, Chantal, Takács-Novák, Krisztina, Grégoire, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625559/
https://www.ncbi.nlm.nih.gov/pubmed/34834173
http://dx.doi.org/10.3390/pharmaceutics13111758