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Use of an In Vitro Skin Parallel Artificial Membrane Assay (Skin-PAMPA) as a Screening Tool to Compare Transdermal Permeability of Model Compound 4-Phenylethyl-Resorcinol Dissolved in Different Solvents
Absorption through the skin of topically applied chemicals is relevant for both formulation development and safety assessment, especially in the early stages of development. However, the supply of human skin is limited, and the traditional in vitro methods are of low throughput. As an alternative, a...
Autores principales: | Sinkó, Bálint, Bárdos, Vivien, Vesztergombi, Dániel, Kádár, Szabina, Malcsiner, Petra, Moustie, Anne, Jouy, Chantal, Takács-Novák, Krisztina, Grégoire, Sebastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625559/ https://www.ncbi.nlm.nih.gov/pubmed/34834173 http://dx.doi.org/10.3390/pharmaceutics13111758 |
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