Cargando…

Efficacy of Ursolic Acid-Enriched Water-Soluble and Not Cytotoxic Nanoparticles against Enterococci

Ursolic acid (UA), a pentacyclic triterpenoid acid found in many medicinal plants and aromas, is known for its antibacterial effects against multi-drug-resistant (MDR) Gram-positive bacteria, which seriously threaten human health. Unfortunately, UA water-insolubility, low bioavailability, and system...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schito, Anna Maria, Caviglia, Debora, Piatti, Gabriella, Zorzoli, Alessia, Marimpietri, Danilo, Zuccari, Guendalina, Schito, Gian Carlo, Alfei, Silvana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625572/ https://www.ncbi.nlm.nih.gov/pubmed/34834390 http://dx.doi.org/10.3390/pharmaceutics13111976

Ejemplares similares

Bactericidal Activity of Non-Cytotoxic Cationic Nanoparticles against Clinically and Environmentally Relevant Pseudomonas spp. Isolates
por: Schito, Anna Maria, et al.
Publicado: (2021)

Pyrazole-Based Water-Soluble Dendrimer Nanoparticles as a Potential New Agent against Staphylococci
por: Alfei, Silvana, et al.
Publicado: (2021)

A Self-Forming Hydrogel from a Bactericidal Copolymer: Synthesis, Characterization, Biological Evaluations and Perspective Applications
por: Alfei, Silvana, et al.
Publicado: (2022)

Potent and Broad-Spectrum Bactericidal Activity of a Nanotechnologically Manipulated Novel Pyrazole
por: Alfei, Silvana, et al.
Publicado: (2022)

Considerable Improvement of Ursolic Acid Water Solubility by Its Encapsulation in Dendrimer Nanoparticles: Design, Synthesis and Physicochemical Characterization
por: Alfei, Silvana, et al.
Publicado: (2021)

Bactericidal Activity of a Self-Biodegradable Lysine-Containing Dendrimer against Clinical Isolates of Acinetobacter Genus
por: Alfei, Silvana, et al.
Publicado: (2021)

Synthesis, Characterization and Broad-Spectrum Bactericidal Effects of Ammonium Methyl and Ammonium Ethyl Styrene-Based Nanoparticles
por: Alfei, Silvana, et al.
Publicado: (2022)

Broad-Spectrum Bactericidal Activity of a Synthetic Random Copolymer Based on 2-Methoxy-6-(4-Vinylbenzyloxy)-Benzylammonium Hydrochloride
por: Schito, Anna Maria, et al.
Publicado: (2021)

Enhanced Antibacterial Activity of a Cationic Macromolecule by Its Complexation with a Weakly Active Pyrazole Derivative
por: Schito, Anna Maria, et al.
Publicado: (2022)

Pyrazole-Enriched Cationic Nanoparticles Induced Early- and Late-Stage Apoptosis in Neuroblastoma Cells at Sub-Micromolar Concentrations
por: Zuccari, Guendalina, et al.
Publicado: (2023)

Mutual Jellification of Two Bactericidal Cationic Polymers: Synthesis and Physicochemical Characterization of a New Two-Component Hydrogel
por: Alfei, Silvana, et al.
Publicado: (2022)

Synthesis, Characterization, and Bactericidal Activity of a 4-Ammoniumbuthylstyrene-Based Random Copolymer
por: Alfei, Silvana, et al.
Publicado: (2021)

A Highly Efficient Polystyrene-Based Cationic Resin to Reduce Bacterial Contaminations in Water
por: Schito, Anna Maria, et al.
Publicado: (2022)

Increased Water-Solubility and Maintained Antioxidant Power of Resveratrol by Its Encapsulation in Vitamin E TPGS Micelles: A Potential Nutritional Supplement for Chronic Liver Disease
por: Zuccari, Guendalina, et al.
Publicado: (2021)

Nanotechnological Manipulation of Nutraceuticals and Phytochemicals for Healthy Purposes: Established Advantages vs. Still Undefined Risks
por: Alfei, Silvana, et al.
Publicado: (2021)

Preparation and Characterization of Amorphous Solid Dispersions for the Solubilization of Fenretinide
por: Zuccari, Guendalina, et al.
Publicado: (2023)

Synthesis and Characterization of Pyrazole-Enriched Cationic Nanoparticles as New Promising Antibacterial Agent by Mutual Cooperation
por: Alfei, Silvana, et al.
Publicado: (2022)

Preparation and Physicochemical Characterization of Water-Soluble Pyrazole-Based Nanoparticles by Dendrimer Encapsulation of an Insoluble Bioactive Pyrazole Derivative
por: Alfei, Silvana, et al.
Publicado: (2021)

Synthesis and Antibacterial Activity of Cationic Amino Acid-Conjugated Dendrimers Loaded with a Mixture of Two Triterpenoid Acids
por: Schito, Anna Maria, et al.
Publicado: (2021)

Synthetic Pathways to Non-Psychotropic Phytocannabinoids as Promising Molecules to Develop Novel Antibiotics: A Review
por: Alfei, Silvana, et al.
Publicado: (2023)

Antibacterial Activity of Non-Cytotoxic, Amino Acid-Modified Polycationic Dendrimers against Pseudomonas aeruginosa and Other Non-Fermenting Gram-Negative Bacteria
por: Schito, Anna Maria, et al.
Publicado: (2020)

Mini-Tablets: A Valid Strategy to Combine Efficacy and Safety in Pediatrics
por: Zuccari, Guendalina, et al.
Publicado: (2022)

4-Hydroxybenzoic Acid as an Antiviral Product from Alkaline Autoxidation of Catechinic Acid: A Fact to Be Reviewed
por: Alfei, Silvana, et al.
Publicado: (2022)

Correction: Alfei et al. 4-Hydroxybenzoic Acid as an Antiviral Product from Alkaline Autoxidation of Catechinic Acid: A Fact to Be Reviewed. Plants 2022, 11, 1822
por: Alfei, Silvana, et al.
Publicado: (2023)

Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems
por: Brullo, Chiara, et al.
Publicado: (2022)

From Nanobiotechnology, Positively Charged Biomimetic Dendrimers as Novel Antibacterial Agents: A Review
por: Alfei, Silvana, et al.
Publicado: (2020)

Positively Charged Polymers as Promising Devices against Multidrug Resistant Gram-Negative Bacteria: A Review
por: Alfei, Silvana, et al.
Publicado: (2020)

β-Lactam Antibiotics and β-Lactamase Enzymes Inhibitors, Part 2: Our Limited Resources
por: Alfei, Silvana, et al.
Publicado: (2022)

Development of Medicines for Rare Pediatric Diseases
por: Marimpietri, Danilo, et al.
Publicado: (2023)

Recommendations to Synthetize Old and New β-Lactamases Inhibitors: A Review to Encourage Further Production
por: Alfei, Silvana, et al.
Publicado: (2022)

One-Step, Low-Cost, Operator-Friendly, and Scalable Procedure to Synthetize Highly Pure N-(4-ethoxyphenyl)-retinamide in Quantitative Yield without Purification Work-Up
por: Alfei, Silvana, et al.
Publicado: (2022)

Correction: Alfei, S.; Zuccari, G. Recommendations to Synthetize Old and New β-Lactamases Inhibitors: A Review to Encourage Further Production. Pharmaceuticals 2022, 15, 384
por: Alfei, Silvana, et al.
Publicado: (2022)

Development of Phytochemical Delivery Systems by Nano-Suspension and Nano-Emulsion Techniques
por: Zuccari, Guendalina, et al.
Publicado: (2023)

Oxidative Stress, Antioxidant Capabilities, and Bioavailability: Ellagic Acid or Urolithins?
por: Alfei, Silvana, et al.
Publicado: (2020)

Successful Dendrimer and Liposome-Based Strategies to Solubilize an Antiproliferative Pyrazole Otherwise Not Clinically Applicable
por: Alfei, Silvana, et al.
Publicado: (2022)

Reshaped as polyester-based nanoparticles, gallic acid inhibits platelet aggregation, reactive oxygen species production and multi-resistant Gram-positive bacteria with an efficiency never obtained
por: Alfei, Silvana, et al.
Publicado: (2019)

Prevention and Eradication of Biofilm by Dendrimers: A Possibility Still Little Explored
por: Alfei, Silvana, et al.
Publicado: (2022)

Dendrimer Nanodevices and Gallic Acid as Novel Strategies to Fight Chemoresistance in Neuroblastoma Cells
por: Alfei, Silvana, et al.
Publicado: (2020)

The Role of the Pharmacist in Selecting the Best Choice of Medication Formulation in Dysphagic Patients
por: Zuccari, Guendalina, et al.
Publicado: (2022)

Cationic Polystyrene-Based Hydrogels: Low-Cost and Regenerable Adsorbents to Electrostatically Remove Nitrites from Water
por: Alfei, Silvana, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mm24postclfnqcibhodk18u9hk